Nouveau dispositif pour le refroidissement localise des structures nerveuses

A vestibulothalamic pathway: Electrophysiological demonstration in the cat by localized cooling

“…In the thalamus unitary activities were recorded by steel extracellular microelectrodes. The vestibulothalamic ascending pathways were traced stereotaxically by means of a cooling thermode of 0.9 mm diam corresponding to the technical characteristics described by Benita (1972). In this sort of experiment the tip of the thermode is practically instantaneously regulated to temperatures from 5°C to lO"C, monitored by means of a thermocouple.…”

Focal Cooling for Drug-Resistant Epilepsy

“…The devices used to apply focal cooling and monitor its effects in animal studies vary widely . One group built an extradural thermoelectric device that detected seizures, applied effective cooling, and then terminated seizures .…”

Impairments and Recovery of the Spatial and Temporal Components of a Visuomotor Pointing Movement after Unilateral Destruction of the Dentate Nucleus in the Baboon

“…During the preparatory phase reaction times always increased during the dentate nucleus cooling. During the ex ecution phase, in subjects deprived of the dentate nucleus control, the ex ecution time was largely modified and significant spatial errors appeared.The cooling method [3,4] involving temporary and reversible block age of the nervous structures does not permit observation of possible functional recovery which can, however, be studied after irreversible le sions. It has been demonstrated that lesions of the dentate nucleus do not involve any lasting cerebellar perturbation, as they disappear about 2 weeks after the dentate nucleus exclusion [5,10,15,17,21,27], The purpose of the present study was to determine the occurrence and rate of ' This investigation was supported by Inserm giant 29.76.61.…”