Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties

Uracil: A Pharmacophore with Diverse Biological Potential

“…Paramonova et al [68] synthesised a series of 1- Geisman et al [69] developed a new method for the synthesis of series of 1 Fang et al [70]…”

“…Paramonova et al [68] . synthesised a series of 1‐[5‐(4‐bromophenoxy)pentyl]‐3‐(2‐arylamino‐2‐oxoethyl)uracil 126 a – d .The synthesis of N‐arylamides 126 a – d involved conversion of 1‐[5‐(4‐bromophenoxy)pentyl]uracil 124 to uracil‐3‐acetic acid derivative 125 which on treatment with thionyl chloride followed by condensation of acyl chloride with arylamines in the presence of pyridine resulted in N‐arylamides 126 a – d (Scheme 33).…”

Synthesis, Characterization, and Anticancer Activity (MCF‐7) of Some Acetanilide‐based Heterocycles

“…Literature studies expose that acetanilide derivatives are an important structural backbone of biologically active molecules. They showed various activities such as antimicrobial , antiviral , anthelmintic , anti‐inflammatory , cytotoxic , antifungal, and antibacterial . Moreover, they possess anti‐arthritic , analgesic , antileishmanial , antitumor , and insecticidal properties.…”

Gold-Catalyzed CN Cross-Coupling Reactions of Aryl Iodides with Alkyl Nitriles or Silver Cyanate

“…All the NMR spectra were recorded on Bruker 600M or 400M NMR spectrometers. Chemical shifts (δ) for 1 H NMR (600 or 400 MHz), 13 C NMR (150 or 100 MHz), and 19 F NMR (565 MHz) were given in ppm. 1 H NMR chemical shifts were recorded relative to SiMe 4 (δ 0.00).…”

“…Chemical shifts (δ) for 1 H NMR (600 or 400 MHz), 13 C NMR (150 or 100 MHz), and 19 F NMR (565 MHz) were given in ppm. 1 H NMR chemical shifts were recorded relative to SiMe 4 (δ 0.00). 13 C NMR chemical shifts were recorded relative to solvent resonance (CDCl 3 : δ 77.16, d-DMSO: 39.6).…”