2015
DOI: 10.1002/jhet.2439
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Novel 7‐Nitro‐1‐(Piperidin‐4‐yl)‐4,5‐Dihydro‐[1,2,4] Triazolo[4,3‐a]Quinoline‐Sulphonamide Derivatives as Antimicrobial Agents: Design, Synthesis, and Bio‐Activity

Abstract: in Wiley Online Library (wileyonlinelibrary.com).In attempt to search for more potent antimicrobial agents, a series of 7-nitro-1-(piperidin-4-yl)-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline-derived sulphonamides were synthesized. Their structures were established by elemental analyses, IR, and NMR ( 1 H and 13 C) spectral data. The antibacterial activity of the obtained compounds was investigated against different Gram-negative (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Bacillus subtilis… Show more

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