The methods, which extract knowledge from Next Generation Sequencing Data (NGS) are highly requested nowadays. The attention to analysis biomedical data is increasing proportionally. In this work, we focus to elicit and discovery a higher amount of knowledge by computing many classification models in a single run, and therefore to identify most of the features related to an investigated class. Major efforts have been made in this field and a last algorithm is proposed" Multiple Part" for data analysis and extraction of new and more knowledge from them. In this paper, we propose a new version of Multiple Part algorithm which integrates a heuristic evaluation method and a feature elimination technique in order to extract multiple and equivalent solution for biomedical data. In order to prove the validity of our algorithm, we analyze an RNA-seq of cancer diseases data sets extracted from The Cancer Genome Atlas (TCGA). Furthermore, we validate our approach by comparing it with the existing methods. Experimental results show the efficacy of our proposed algorithm.