2007
DOI: 10.1055/s-2007-991093
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Novel and Facile Transformation of N,N-Disubstituted Glycylamides into Corresponding Cyanamides by Using Pentavalent Iodine Reagents in Combination with Tetraethylammonium Bromide

Abstract: Novel and facile transformation of N,N-disubstituted glycylamides into corresponding cyanamides using pentavalent iodine reagents and tetraethylammonium bromide is discussed. The advantages of this system are use of non toxic reagents, shorter reaction times and moderate to good yields.

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Cited by 9 publications
(2 citation statements)
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“…[14] Later, cyanamides have constructed using desulfurizing agent [16,17] and iodinating reagent. [18,19] Some other methods are known for the preparation of cyanamides. [20] However most of the reported methods having drawbacks namely, (i) using toxic reagents, (ii) using alkaline conditions, (iii) using very cost materials and harsh conditions (v) giving low yields.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…[14] Later, cyanamides have constructed using desulfurizing agent [16,17] and iodinating reagent. [18,19] Some other methods are known for the preparation of cyanamides. [20] However most of the reported methods having drawbacks namely, (i) using toxic reagents, (ii) using alkaline conditions, (iii) using very cost materials and harsh conditions (v) giving low yields.…”
Section: Introductionmentioning
confidence: 99%
“…Alternatively they have prepared from urea's and thioureas using transition metals [14] . Later, cyanamides have constructed using desulfurizing agent [16,17] and iodinating reagent [18,19] …”
Section: Introductionmentioning
confidence: 99%