Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis

Verallo-Rowell, Vermén M.; Dillague, Kristine M; Syah-Tjundawan, Bertha S

doi:10.2310/6620.2008.08052

Cited by 150 publications

(122 citation statements)

References 22 publications

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“…All groups were significant compared to untreated control on day 7 (p≤0.0001). Independent antimicrobial effects can be attributed to CO, as shown previously, 27 but were significantly enhanced by addition of curc-np.…”

Section: Resultssupporting

confidence: 72%

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

Krausz

Adler

Cabral

et al. 2015

Nanomedicine: Nanotechnology, Biology and Medicine

424

273

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Burn wounds are often complicated by bacterial infection, contributing to morbidity and mortality. Agents commonly used to treat burn wound infection are limited by toxicity, incomplete microbial coverage, inadequate penetration, and rising resistance. Curcumin is a naturally derived substance with innate antimicrobial and wound healing properties. Acting by multiple mechanisms, curcumin is less likely than current antibiotics to select for resistant bacteria. Curcumin's poor aqueous solubility and rapid degradation profile hinder usage; nanoparticle encapsulation overcomes this pitfall and enables extended topical delivery of curcumin. In this study, we synthesized and characterized curcumin nanoparticles (curc-np), which inhibited in vitro growth of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa in dose-dependent fashion, and inhibited MRSA growth and enhanced wound healing in an in vivo murine wound model. Curc-np may represent a novel topical antimicrobial and wound healing adjuvant for infected burn wounds and other cutaneous injuries.

show abstract

Section: Resultssupporting

confidence: 72%

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

Krausz

Adler

Cabral

et al. 2015

Nanomedicine: Nanotechnology, Biology and Medicine

424

273

View full text Add to dashboard Cite

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“…In addition, it has also been shown to address another important aspect of atopic dermatitis: staphylococcal colonization. In a randomized controlled trial it was found to clear an impressive 95% of staphyoloccal colonization in patients with AD (Verallo-Rowell et al 2008 ). And, similar to the findings of sunflower seed oil, VCO has been shown to improve barrier function in low birthweight babies (Nangia et al 2008 ).…”

Section: Evidence For Sunflower Seed Oilmentioning

confidence: 65%

Handbook of Integrative Dermatology

Lio¹,

Patel²,

Peters³

et al. 2015

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“…[22] Recent studies have shown that coconut oil has antimicrobial activity against various gram positive and gram negative organisms such as Escherichia vulneris , Enterococcer spp , Helicobater pylori , Staphylococcus aureus , Streptococcus mutans , and Candia albicans . [232425]…”

Section: Discussionmentioning

confidence: 99%

Comparison of antibacterial efficacy of coconut oil and chlorhexidine on Streptococcus mutans: An : An in vivo study study

Peedikayil

Remy

John

et al. 2016

J Int Soc Prevent Communit Dent

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Aims:Streptococcus mutans is the most common organism causing dental caries. Various chemotherapeutic agents are available that help in treating the bacteria, with each having their own merits and demerits. Recent research has shown that coconut oil has anti-inflammatory and antimicrobial action. Therefore, the present was conducted to determine the antibacterial efficacy of coconut oil and to compare it with chlorhexidine.Materials and Methods:A total of fifty female children aged 8–12 years were included in the study. Twenty five children were randomly distributed to each group, i.e., the study group (coconut oil) and the control group (chlorhexidine). The participants were asked to routinely perform oil swishing with coconut oil and chlorhexidine and rinse every day in the morning after brushing for 2–3 minutes. S. mutans in saliva and plaque were determined using a chairside method, i.e., the Dentocult SM Strip Mutans test. Patients were instructed to continue oil swishing for 30 days. S. mutans. counts in plaque and saliva on day 1, day 15, and day 30 were recorded and the results were compared using Wilcoxon matched pairs signed ranks test.Results:The results showed that there is a statistically significant decrease in S. mutans. count from coconut oil as well as chlorhexidine group from baseline to 30 days. The study also showed that in comparison of coconut oil and chlorhexidine there is no statistically significant change regarding the antibacterial efficacy.Conclusion:Coconut oil is as effective as chlorhexidine in the reduction of S. mutans.

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Novel Antibacterial and Emollient Effects of Coconut and Virgin Olive Oils in Adult Atopic Dermatitis

Cited by 150 publications

References 22 publications

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

Handbook of Integrative Dermatology

Comparison of antibacterial efficacy of coconut oil and chlorhexidine on Streptococcus mutans: An : An in vivo study study

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