Novel Application of Post-contrast T₁map for Detection of Subendocardial Infarction

Abstract

In cardiac magnetic resonance (CMR) for myocardial infarction, there have been quite a few cases of obscure image contrast between subendocardial lesion and left ventricular (LV) blood pool on late gadolinium enhancement (LGE) images. This study was motivated by confirmation of usefulness of post-contrast T 1 map for detection of subendocardial infarction. From June 2017 to May 2018, forty-eight consecutive patients who underwent contrast-enhanced CMR to assess myocardial infarction were reviewed. We measured the contrast ratio (CR) between the infarcted myocardium and LV blood pool on LGE and on post-contrast T 1 map images, and compared them. The CR (mean±standard deviation) was −0.04±0.11 for LGE images and 0.02±0.04 for post-contrast T 1 map images (P<0.05). These results suggest that the post-contrast T 1 map, which uses the difference in T 1 value as image contrast rather than magnitude image, can clearly depict the boundary between the infarcted myocardium and LV blood pool. The addition of post-contrast T 1 map to image interpretation might provide valuable information in the evaluation of subendocardial infarction.