Novel block copolymers of atactic PHB with natural PHA for cardiovascular engineering: Synthesis and characterization

Enhancement of poly(3-hydroxybutyrate) thermal and processing stability using a bio-waste derived additive

“…synthesis of copolyesters containing different PHAs units other than PHB, by using different bacterial strains or chemical synthesis routes [11,12]. Furthermore, blending of PHB with high or low molecular weight components, such as suitable organic and inorganic additives, represents another approach to provide both an upgrading of processing and manufacturing performance, and a relative inexpensive strategy to enhance polymer physical properties [13][14][15][16][17][18].…”

Synthetic routes to degradable copolymers deriving from the biosynthesized polyhydroxyalkanoates: A mini review

“…PHAs macroinitiators containing olefinic and carboxylic end groups were obtained by the controlled depolymerization of natural PHAs (PHB, PHBV or PHO), being catalyzed by KOH/18-crown-6 complex in a CHCl 3 / H 2 O system. These macroinitiators, having similar molecular mass (M n = 3000) and a unimodal molecular mass distribution, were then used in anionic ROP of !-butyrolactone to obtain the respective diblock copolymers of natural origin PHA and a-PHB [105][106][107].…”

“…It should be noted that the toxic nature of stannous ethylhexanoate is a big obstacle for its use Figure 5. Scheme of the two-step synthesis of the PHB-PLA-PCL triblock copolymer through ring opening polymerization PHA-(a-PHB) PHA:PHB, PHBV, PHO Anionic ROP [105][106][107] in biomedical application, though it has been granted as a food additive by FDA. Another problem is the rather low rate of ROP.…”

A novel method for the determination of diffusion coefficients in amorphous poly(3-hydroxybutyrate)

“…Using it in medical and generally in vivo applications [5][6][7][8][9][10][11][12][13] seems to be obvious, since the polymer yields only nontoxic metabolites [14][15][16][17]. One of the most important and most intensively studied area is the use of poly(3-hydroxybutyrate) as drug carrier matrix [18][19][20][21][22][23].…”