2023
DOI: 10.1002/mnfr.202200726
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Novel Calcium‐Binding Peptide from Bovine Bone Collagen Hydrolysates and Its Potential Pro‐Osteogenic Activity via Calcium‐Sensing Receptor (CaSR)

Liwei Qi,
Hongru Zhang,
Yujie Guo
et al.

Abstract: ScopeThis paper aims to explore the osteogenic activity and potential mechanism of the peptide‐calcium chelate, and provides a theoretical basis for peptide‐calcium chelates as functional foods to prevent or improve osteoporosis.Methods and resultsIn this research, a novel peptide (Phe‐Gly‐Leu, FGL) with a high calcium‐binding capacity is screened from bovine bone collagen hydrolysates (CPs), calcium binding sites of which mainly included carbonyl, amino and carboxyl groups. The FGL‐Ca significantly enhances t… Show more

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