Novel catalytic acetylation and formylation of alcohols with potassium dodecatungstocobaltate trihydrate (K5CoW12O40·3H2O)

The direct condensation of various carboxylic acids and alcohols was achieved efficiently at reflux temperature under a solvent free condition using a catalytic amount of tetrabutylammonium tribromide (TBATB). Chemoselective acylation of primary alcohols in presence of secondary alcohols and phenols has been achieved. Steric factors in carboxylic acids played a crucial role during chemoselective acylation of diols. Reaction under a solvent free condition, absence of any dehydrating agent or use of any special techniques for removal of water and higher yields are the important features of this protocol.

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“…1 H NMR (300 MHz, CDCl 3 ) δ 0.88 (t, 3H, J = 6.9 Hz), 1.26 (m, 18H), 1.62 (m, 2H), 2.04 (s, 3H), 4.05 (t, 2H, J = 6.6 Hz) ppm. 13 …”

Section: Arkatmentioning

confidence: 99%

Tetrabutylammonium tribromide mediated condensation of carboxylic acids with alcohol

Naik¹,

Kavala²,

Gopinath³

et al. 2005

Arkivoc

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“…A variety of catalysts have been used for activating this reagents, such as Sc(OTf) 3 and Sc(NTf 2 ) 3 [21], TiCl(OTf) 3 [22], TMSCl and TMSOTf [23], La(i-Pr) 3 [24], COCl 2 [25], Sn(OTf) 2 [26], TiCl 4 and AgClO 4 [27], AlPW 12 O 40 [28], PCl 3 -n(SiO 2 ) n [29], PPh 3 /CBr 4 [30] [32] and ZnO [33].…”

Section: Introductionmentioning

confidence: 99%

Poly(N,N′-dichloro-N-ethyl-benzene-1,3-disulfonamide, N,N,N′,N′-tetrachlorobenzene-1,3-disulfonamide, poly(N,N′-dibromo-N-ethyl-benzene-1,3-disulfonamide, and N,N,N′,N′-tetrabromobenzene-1,3-disulfonamide catalyzed formylation of amines and alcohols using ethyl formate under microwave irradiation

Ghorbani‐Vaghei

Veisi

Amiri

2009

JICS

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“…3 Further PDTC was successfully used in various organic transformations including esterification and transesterification, regeneration of carbonyl compounds from oximes, and synthesis of substituted 3,4-dihydropyrimidin-2(1H)-ones, quinolines, dihydroquinolines, pyridines, imidazoles and xanthenes.…”

Section: Introductionmentioning

confidence: 99%

Potassium Dodecatungstocobaltate Trihydrate: K5CoW12O40×3H2O

Chary¹

2009

Synlett

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This feature focuses on a reagent chosen by a postgraduate, highlighting the uses and preparation of the reagent in current research Potassium Dodecatungstocobaltate Trihydrate: K 5 CoW 12 O 40 •3H 2 O Compiled by M. Venu Chary M. Venu Chary was born in Uddemarry, Andhra Pradesh, India, in 1976. He obtained his M.Sc. in Organic Chemistry from Kakatiya University, Warangal, in 2001. After working for one year as Junior Chemist in Thioxazo Biotech Laboratory Pvt. Ltd., Hyderabad, he joined the Indian Institute of Chemical Technology as Junior Research Fellow. He is currently working towards his Ph.D. under the supervision of Dr. D. Subhas Bose on the total synthesis of (-)-circumdatin H. His research interests focus on the synthesis of bioactive natural products, process development work, and development of new synthetic methodologies.

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Novel catalytic acetylation and formylation of alcohols with potassium dodecatungstocobaltate trihydrate (K5CoW12O40·3H2O)

Cited by 58 publications

References 37 publications

Tetrabutylammonium tribromide mediated condensation of carboxylic acids with alcohol

Tetrabutylammonium tribromide mediated condensation of carboxylic acids with alcohol

Potassium Dodecatungstocobaltate Trihydrate: K5CoW12O40×3H2O

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