2019
DOI: 10.1530/endoabs.63.p185
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Novel clusters of adult-onset Diabetes: Casuistic from an Endocrinology Department

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“…Efforts have been made in various populations to identify distinct "clusters" of phenotypic characteristics and laboratory markers in individuals diagnosed with T2D, and to assess whether these clusters correlate with differential risk of diabetes complications [2,3]. A pioneering study by Ahlquist et al [2] in a Scandinavian population, led to the identification of five major subtypes of T2D termed as Severe Autoimmune Diabetes (SAID), Severe Insulin Deficient Diabetes (SIDD), Severe Insulin Resistant Diabetes (SIRD), Mild Obesity-related Diabetes (MOD) and Mild Age-Related Diabetes (MARD).This was also reproduced in several other ethinic groups [4][5][6].…”
Section: Introductionmentioning
confidence: 97%
“…Efforts have been made in various populations to identify distinct "clusters" of phenotypic characteristics and laboratory markers in individuals diagnosed with T2D, and to assess whether these clusters correlate with differential risk of diabetes complications [2,3]. A pioneering study by Ahlquist et al [2] in a Scandinavian population, led to the identification of five major subtypes of T2D termed as Severe Autoimmune Diabetes (SAID), Severe Insulin Deficient Diabetes (SIDD), Severe Insulin Resistant Diabetes (SIRD), Mild Obesity-related Diabetes (MOD) and Mild Age-Related Diabetes (MARD).This was also reproduced in several other ethinic groups [4][5][6].…”
Section: Introductionmentioning
confidence: 97%
“…In recent years, efforts have been made for identifying "clusters" or subgroups of individuals with diabetes mellitus using different clinical and biochemical variables, which exhibit diverse phenotypic, clinical, and risk of complications behaviors. (4)(5)(6)(7) Trials for new classification of diabetes of the adults In 2015, Li.L et al attempted to categorize various sub-types from diabetes mainly type 2 patients using topological analysis of patient cohort. (8) This was the beginning of recent trials for discovering new categorizations of type 2 DM.…”
Section: Introductionmentioning
confidence: 99%