Novel coronavirus infection (COVID-19): epidemiology, clinical characteristics of patients, risk of complications, prevention, use of selenium-containing drugs

Dedov, D.

doi:10.29296/25877305-2022-05-12

Врач

2022

DOI: 10.29296/25877305-2022-05-12

|View full text |Cite

Novel coronavirus infection (COVID-19): epidemiology, clinical characteristics of patients, risk of complications, prevention, use of selenium-containing drugs

D. Dedov

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Markov model in evaluating the efficiency of various COVID-19 treatment regimens

Vdoushkina,

Borodulina,

Gladunova

et al. 2023

Vrach

View full text Add to dashboard Cite

Objective. To consider the evidence-based approaches to treating virus-associated lung tissue lesions, the rationale for using the Markov model to evaluate the clinical and economic efficacy of interleukin (IL)-6 (IL-6) receptor inhibitors in patients with COVID-19. Subjects and methods. To evaluate the clinical and economic effectiveness of using the receptor inhibitors in COVID-19 patients, the investigators formed two groups: 1) 187 patients received the standard therapy; 2) 104 patients had IL-6 receptor inhibitors in addition to the standard therapy. Results and conclusion. The logistic regression method was used to determine the need for prescribing these drugs depending on the individual characteristics of patients, the key points were the length of a patient's stay in the intensive care unit, as well as the duration of oxygen support. In the context of new challenges to the healthcare system, it is necessary to further search for comprehensive methods of monitoring the condition and prognosis with promising ways to assess the validity of using therapeutic procedures and drugs.

show abstract

Markov model in evaluating the efficiency of various COVID-19 treatment regimens

Vdoushkina,

Borodulina,

Gladunova

et al. 2023

Vrach

View full text Add to dashboard Cite

show abstract

Finding non-toxic form of selenium

Полубояринов

Sergeeva-Kondrachenko

Vinogradova

et al. 2023

Medicinskij alfavit

View full text Add to dashboard Cite

Selenium is a vital trace element, a key agent in the functioning of the human antioxidant system. Maintaining its optimal level in the body prevents the development of a wide range of pathologies and disorders in the functioning of the endocrine, cardiovascular, reproductive, nervous and other systems. Deﬁciency of this microelement is observed in 50% of Russians, reaching 95–100% in some regions. Therefore, the correction of selenium status is an urgent task of public health, in connection with which research is underway on various selenium compounds that differ in efﬁciency, degree of bioavailability and toxicity. The most appropriate human physiology, well-absorbed, effective and safe form of selenium is the amino acid l-selenocystin (selenocysteine in a reduced state). This is what formed the basis of the Parafarm drug SELENBIO for women, which allows compensating for selenium deﬁciency in different categories of the population without the risk of intoxication.

show abstract

Impact of COVID-19 vaccination on the severity of the course and outcomes of the disease in hospitalized patients in St. Petersburg

Nechaev,

Zaguzov,

Lyalina

2024

Sanitary Doctor

View full text Add to dashboard Cite

Vaccination against infection caused by the SARS-CoV-2 virus, despite the problems of a biological and social nature, remains the main preventive measure to prevent the spread of this infection. The aim is to assess the effect of COVID-19 vaccine prophylaxis on the incidence of severe forms and deaths among hospitalized patients. A retrospective epidemiological analysis of official data on 13,778 patients hospitalized in the main repurposed hospitals of the city of St. Petersburg was carried out, of which 973 people had a fatal disease. The frequency of pneumonia and deaths among vaccinated and unvaccinated patients was analyzed. Correlation and regression analysis was used to determine the nature of the relationship between these factors. An analysis of the incidence of pneumonia and deaths in patients with different vaccination status showed their statistically significant predominance among unvaccinated patients (p < 0.05). Quantitative fluctuations in deaths in 2021–2022 were established due to the beneficial effect of preventive vaccinations against COVID-19, expressed in a decrease in hospital mortality rates. The greatest reduction in mortality was achieved in the group of vaccinated patients in the absence of pneumonia. The risk of adverse outcomes was highest in the presence of pneumonia and the absence of vaccinations. A significant favorable factor was the vaccination coverage of hospitalized patients. COVID-19 vaccine prophylaxis has a positive effect on both the severity of this infection and its outcomes. However, a critical factor in this case is the degree of immunization of the population.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Novel coronavirus infection (COVID-19): epidemiology, clinical characteristics of patients, risk of complications, prevention, use of selenium-containing drugs

Cited by 3 publications

References 0 publications

Markov model in evaluating the efficiency of various COVID-19 treatment regimens

Markov model in evaluating the efficiency of various COVID-19 treatment regimens

Finding non-toxic form of selenium

Impact of COVID-19 vaccination on the severity of the course and outcomes of the disease in hospitalized patients in St. Petersburg

Contact Info

Product

Resources

About