Novel drug delivery nanosystems based on out-inside bifunctionalized mesoporous silica yolk–shell magnetic nanostars used as nanocarriers for curcumin

Abstract

Bifunctionalized yolk–shell magnetic mesoporous silica is used as a curcumin nanocarrier with magnetic response and increased cellular uptake.

Electrospray biodegradable microcapsules loaded with curcumin for drug delivery systems with high bioactivity

“…The main peaks of Cur were also seen in C 10 PLA, which could be concluded as the successful immobilization of cargoes inside the PLA-based vehicles. 3,4 XRD X-ray diffraction experiments were performed to assess the crystallinity of each samples, i.e., C 0 PLA, pure Cur and C 10 PLA.…”

“…It has various biological applications such as antioxidant, anti-cancer, antimicrobial, antiphlogosis and antilipidemic effect. 3,4 However, curcumin molecules were found to be unstable to a variety of physical and chemical environments, e.g., heat, pH, light or alkali medium. Furthermore, its poor water solubility results in lower bioavailability, restricting its practical clinical trials.…”

Emerging Nanoclay Composite for Effective Hemostasis

“…Several topical hemostats based on organic polymers and inorganic micro‐/nanometer materials have been developed . Since the U.S. Food and Drug Administration (FDA) approved QuikClot, a zeolite‐based externally applied hemostat in 2002, there has been considerable interest in natural nanoclay minerals for the management of massive hemorrhage–especially for battlefield trauma–owing to their high absorption and biological inertness . In our previous studies, clay minerals, such as kaolinite, montmorillonite, and halloysite have exhibited attractive physicochemical properties in catalytic, adsorption, and energy storage .…”

Paclitaxel prodrug based mixed micelles for tumor-targeted chemotherapy

“…Apart from the steadily delivering and controlled release properties, hemolysis of the drug-loaded MMs was also investigated as a safety guide for intravenous administration and medicinal application. 31 As shown in Fig. 3B, the drug-loaded MMs displayed no or neglectable hemolysis (merely 1.79%) on RBCs at the highest concentration of 1 mg mL À1 .…”