Novel electrochemical genosensor for Zika virus based on a poly-(3-amino-4-hydroxybenzoic acid)-modified pencil carbon graphite electrode

Alves, Rafael da Fonseca; Franco, Diego Leoni; Cordeiro, Marli Tenório; Júnior, Ernesto Marques de Oliveira; Dutra, Rosa Amália Fireman; Sotomayor, Marı́a Del Pilar Taboada

doi:10.1016/j.snb.2019.126681

Cited by 37 publications

(18 citation statements)

References 48 publications

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“…The detection of Zika virus (ZIKV) sometimes becomes a major problem because of the cross-responses between zika and dengue viruses. A DNA based biosensor for the detection of ZIKV was revealed by Alves et al using poly(3-amino-4-hydroxybenzoic acid) modified pencil carbon graphite electrode, which was superior over immunosensors in terms of low cost and its simple modification procedure [ 48 ]. They have validated the bioassay in human serum samples.…”

Section: Review Of Recent Electrochemical Biosensors For Eids and Re-mentioning

confidence: 99%

Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

Menon

Mathew

Sam

et al. 2020

Journal of Electroanalytical Chemistry

152

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The rise of emerging infectious diseases (EIDs) as well as the increase in spread of existing infections is threatening global economies and human lives, with several countries still fighting repeated onslaught of a few of these epidemics. The catastrophic impact a pandemic has on humans and economy should serve as a reminder to be better prepared to the advent of known and unknown pathogens in the future. The goal of having a set of initiatives and procedures to tackle them is the need of the hour. Rapid detection and point-of-care (POC) analysis of pathogens causing these diseases is not only a problem entailing the scientific community but also raises challenges in tailoring appropriate treatment strategies to the healthcare sector. Among the various methods used to detect pathogens, Electrochemical Biosensor Technology is at the forefront in the development of POC devices. Electrochemical Biosensors stand in good stead due to their rapid response, high sensitivity and selectivity and ease of miniaturization to name a few advantages. This review explores the innovations in electrochemical biosensing based on the various electroanalytical techniques including voltammetry, impedance, amperometry and potentiometry and discusses their potential in diagnosis of emerging and re-emerging infectious diseases (Re-EIDs), which are potential pandemic threats.

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Section: Review Of Recent Electrochemical Biosensors For Eids and Re-mentioning

confidence: 99%

Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

Menon

Mathew

Sam

et al. 2020

Journal of Electroanalytical Chemistry

152

View full text Add to dashboard Cite

show abstract

“…In recent years, many researchers have applied EIS for the determination of specific pathogenic flaviviruses [55][56][57]. This method stands out among other electrochemical methods, since the analysis proceeds without irreversible changes in the electrode material, and does not require a high consumption of chemical reagents [58].…”

Section: Electrochemical Impedance Spectroscopy and Conductometrymentioning

confidence: 99%

“…Different materials can improve conductive properties of biosensors and thus increase their sensitivity. Various research groups reported the possibility of functionalization of electrode surfaces by polymeric materials or used them as platforms for ZIKV detection [26,48,56]. Polymeric films are also perfect materials for the conjugation with biomolecules, since they can be chemically functionalized [114].…”

Section: Electrochemical Biosensors For Zikv Diagnosticmentioning

confidence: 99%

“…In this work, ZIKV was quantified via DPV, with LOD down to 0.1 fg/mL, showing good stability and great potential for further practical diagnostic of ZIKV ( Figure 5). Based on the same principles, Alves and co-workers described the formation of a polymeric film derived from 3-amino-4-hydroxybenzoic acid (3-4-AHBA) on the surface of a pencil carbon graphite electrode (PCGE) for quantitative monitoring of ZIKV [56]. A proposed platform can differentiate cross-responses between DENV and ZIKV in enriched human serum.…”

Section: Electrochemical Biosensors For Zikv Diagnosticmentioning

confidence: 99%

“…It is based on the immobilization of surface imprinted polymers (SIPs) and GO composites at the AuE surface for detecting of ZIKV antigen. In general, SIPs have very high electrical resistance, but by adding nanocarbon materials Based on the same principles, Alves and co-workers described the formation of a polymeric film derived from 3-amino-4-hydroxybenzoic acid (3-4-AHBA) on the surface of a pencil carbon graphite electrode (PCGE) for quantitative monitoring of ZIKV [56]. A proposed platform can differentiate cross-responses between DENV and ZIKV in enriched human serum.…”

Section: Electrochemical Biosensors For Zikv Diagnosticmentioning

confidence: 99%

See 2 more Smart Citations

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

Khristunova

Dorozhko

Короткова

et al. 2020

Sensors

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A highly effective way to improve prognosis of viral infectious diseases and to determine the outcome of infection is early, fast, simple, and efficient diagnosis of viral pathogens in biological fluids. Among a wide range of viral pathogens, Flaviviruses attract a special attention. Flavivirus genus includes more than 70 viruses, the most familiar being dengue virus (DENV), Zika virus (ZIKV), and Japanese encephalitis virus (JEV). Haemorrhagic and encephalitis diseases are the most common severe consequences of flaviviral infection. Currently, increasing attention is being paid to the development of electrochemical immunological methods for the determination of Flaviviruses. This review critically compares and evaluates recent research progress in electrochemical biosensing of DENV, ZIKV, and JEV without labelling. Specific attention is paid to comparison of detection strategies, electrode materials, and analytical characteristics. The potential of so far developed biosensors is discussed together with an outlook for further development in this field.

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Ultrasensitive Nano-Biosensors for Virus Detection

Hegazy,

Elbadry,

Sayed

et al. 2023

Handbook of Nanosensors

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Novel electrochemical genosensor for Zika virus based on a poly-(3-amino-4-hydroxybenzoic acid)-modified pencil carbon graphite electrode

Cited by 37 publications

References 48 publications

Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases

Label-Free Electrochemical Biosensors for the Determination of Flaviviruses: Dengue, Zika, and Japanese Encephalitis

Ultrasensitive Nano-Biosensors for Virus Detection

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