Novel energy source for ablating the pulmonary veins; Is pulsed field ablation the new ablation modality?

Ishidoya, Yuki; Ranjan, Ravi

doi:10.1111/jce.14982

Cited by 1 publication

(2 citation statements)

References 11 publications

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“…The true risks are unknown, although the limited preliminary data are promising. [63] Tissue loss beyond the target tissue Based on the time-dependent conductive thermal mechanism of RFA, the target zone temperature must involve the following to effectively create transmural lesions: (1) the appropriate peak temperature must be reached at the proximal tissue-electrode interface and (2) the peak temperature must spread from the proximal to distal tissues to destroy the tissue transmurally from the endocardium to the epicardium. In general, the crosssectional area of lesions is elliptical, that is, it is larger proximally and smaller distally.…”

Section: Procedures Timementioning

confidence: 99%

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Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges

Xie¹,

Chen²,

Chen

et al. 2022

Cardiology Discovery

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Pulsed electric field (PEF) is a novel energy source by which high-voltage electric pulses are used to create irreversible electroporation. PEF is non-thermal and highly tissue-dependent in which specific targeting of the atrial myocardium is achieved and sparing of adjacent tissues is feasible, theoretically increasing the safety of the procedure, which could potentially break the trade-off between effective lesions and collateral damage and substantially improve risk-benefit ratios in atrial fibrillation (AF) ablation. Although recently published trials have shown a clear effect of AF ablation, large-scale clinical trials are lacking. Current clinical evidence has demonstrated significant efficacy in achieving durable pulmonary vein isolation without ablation-related adverse events. However, their putative benefits regarding efficacy, efficiency, and safety remain to be proven in randomized controlled trials.

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Section: Procedures Timementioning

confidence: 99%

“…Therefore, it is inappropriate to state that each of the risks is definitively lower for IRE ablation than RFA. The true risks are unknown, although the limited preliminary data are promising [63] …”

Section: History Of Irreversible Electroporation (Ire) and Its Applic...mentioning

confidence: 99%

Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges

Xie¹,

Chen²,

Chen

et al. 2022

Cardiology Discovery

View full text Add to dashboard Cite

show abstract

Novel energy source for ablating the pulmonary veins; Is pulsed field ablation the new ablation modality?

Cited by 1 publication

References 11 publications

Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges

Irreversible Electroporation Ablation for Atrial Fibrillation: Status and Challenges

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