Novel Findings in Obstetric Brachial Plexus Palsy: A Study of Corpus Callosum Volumetry and Resting-State Functional Magnetic Resonance Imaging of Sensorimotor Network

Kishore, K.R.; Devi, Bhagavatula Indira; Bhat, Dhananjaya I; Shukla, Dhaval; Gupta, Arun Kumar; Panda, Rajanikant

doi:10.1093/neuros/nyx495

Cited by 10 publications

(2 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, abnormal cortical activation patterns associated with motor imagery tasks have been described in young adults with NBPP, suggestive of motor planning deficits 47 . Further evidence of central alterations in NBPP include reduced corpus callosal volume in motor association areas coupled with decreased activation of sensorimotor networks in both the contra‐ and ipsilateral hemispheres 48 …”

Section: Discussionmentioning

confidence: 99%

“…47 Further evidence of central alterations in NBPP include reduced corpus callosal volume in motor association areas coupled with decreased activation of sensorimotor networks in both the contra-and ipsilateral hemispheres. 48 Therefore, treatment strategies for NBPP in the context of central alterations require evaluation of clinical presentation supplemented with ancillary studies (eg, electro-diagnostic, imaging, etc. )-in addition to serial evaluations of not only WHO-ICF Body Function and Structure domains (eg, ROM and muscle power) but, more important, Activity and Participation domains (eg, functional arm use at home and school).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Quantifying real‐world upper limb activity via patient‐initiated spontaneous movement in neonatal brachial plexus palsy

Gatward

Logue

Yang

et al. 2022

PM&R

View full text Add to dashboard Cite

Background: Neonatal brachial plexus palsy (NBPP) results in muscle weakness and impaired somatosensory function of the arm. Current functional assessment is primarily based on clinician-elicited measurements including muscle strength and range of motion. To what extent these measures are representative of real-world arm movement is unclear. Objective: To determine the feasibility of using body-worn accelerometers to remotely assess arm movements in children with NBPP. Design: Prospective criterion validity study of accelerometry versus clinician assessment. Setting: Academic medical center. Participants: Nine adolescents with NBPP and nine age-and gender-matched control adolescents participated in the study. All were enrolled in school and participated in community activities.Interventions: Not applicable. Methods: Standard clinician-elicited measurements were collected. For assessing spontaneous arm movements, participants wore activity monitors during all waking hours for 7 days. Results were expressed as ratios of affected to unaffected arm motion for duration and magnitude and correlated with traditional clinic-based assessments. Spearman correlations were used to determine relationships between accelerometry results and traditional assessments. A p value <.05 was considered statistically significant. Main Outcome Measurements: Accelerometry measurements of arm motion and traditional clinical assessments. Results: Compared to control ratios, duration of arm movement and magnitude ratios were reduced in the NBPP group, particularly for arm magnitude due to reduced affected arm movement and an increase in unaffected arm movement. Ratios were highly correlated with shoulder function and, to a lesser extent, with elbow function. Conclusion: Real-world arm use is an appropriate outcome measure that reflects functional recovery. This study demonstrates the feasibility of wearable technology to quantify duration and intensity of spontaneous arm movement in children with NBPP. Accelerometry also allows for the association between traditional clinician-elicited assessment measures and spontaneous arm movements, demonstrating the importance of the shoulder as a focus of treatment in NBPP.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%