Novel insights into whey protein differences between donkey and bovine milk

Li, Mohan; Yu, Haikun; Chen, Jiali; Abdlla, Rayhnigul; Liu, Aicheng; Song, Wanying; Zhang, Juan; Zhang, Xiumin; Li, Qilong

doi:10.1016/j.foodchem.2021.130397

Cited by 32 publications

(15 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Proteomics addresses several key issues. For example, the identification and quantification of proteins can facilitate the understanding of the composition of organisms. , Post-translational modifications (PTMs), such as phosphorylation, glycosylation, ubiquitination, and methylation, can provide greater insight into the properties and functions of proteins. , Functional proteomics can connect uncharacterized proteins with proteins with established functions, which provides the basis for future in-depth mechanistic investigations . In recent years, with the development of high-resolution mass spectrometry (MS), proteomic research has constantly been innovated and improved.…”

Section: Proteomes and Peptidomics Profilingmentioning

confidence: 99%

Proteomics and Peptidomics As a Tool to Compare the Proteins and Endogenous Peptides in Human, Cow, and Donkey Milk

Ning,

Yang,

Liu

et al. 2023

J. Agric. Food Chem.

Self Cite

View full text Add to dashboard Cite

Cow’s milk is the most widely used ingredient in infant formulas. However, its specific protein composition can cause allergic reactions. Finding alternatives to replace cow’s milk and fill the nutritional gap with human milk is essential for the health of infants. Proteomic and peptidomic techniques have supported the elucidation of milk’s nutritional ingredients. Recently, omics approaches have attracted increasing interest in the investigation of milk because of their high throughput, precision, sensitivity, and reproducibility. This review offers a significant overview of recent developments in proteomics and peptidomics used to study the differences in human, cow, and donkey milk. All three types of milks were identified to have critical biological functions in human health, particularly in infants. Donkey milk proteins were closer in composition to human milk, were less likely to cause allergic reactions, and may be developed as novel raw materials for formula milk powders.

show abstract

Section: Proteomes and Peptidomics Profilingmentioning

confidence: 99%

Proteomics and Peptidomics As a Tool to Compare the Proteins and Endogenous Peptides in Human, Cow, and Donkey Milk

Ning,

Yang,

Liu

et al. 2023

J. Agric. Food Chem.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Animal proteins are widely recognised for their excellent nutritional value and technological properties, making them a popular choice in the food industry (Li et al 2021a;Xie et al 2023b). However, concerns such as supply and demand conflicts, greenhouse gas emissions, and religious beliefs have led to a growing interest in finding alternative protein sources.…”

Section: Introductionmentioning

confidence: 99%

“…Animal proteins are widely recognised for their excellent nutritional value and technological properties, making them a popular choice in the food industry (Li et al . 2021a; Xie et al . 2023b).…”

Section: Introductionmentioning

confidence: 99%

Physicochemical, structural, and emulsifying properties of stable blended whey and soy protein colloidal dispersion prepared by pH‐shifting and ultrasound

Liu,

Gao,

Xia

et al. 2024

Int J of Dairy Tech

View full text Add to dashboard Cite

This study investigated physiochemical, structural, and emulsifying properties of whey and soy protein blends (4%, w/v), which were combined at various proportions by pH‐shifting and ultrasound. The mixed dispersions exhibited small particle sizes (below 200 nm), with the smallest value observed at a sample with WPC to SPI ratio of 50:50. Reducing whey protein gave the blend lower surface hydrophobicity and higher α‐helix structure. More soy protein resulted in larger droplet size, lower surface charge, and greater flocculation of fabricated emulsions. Emulsions with soy protein lower than 50% were acceptable due to the nano‐scale size and small flocculation index.

show abstract

“…In this sense, the proteome expression differences of colostrum and milk have been studied in humans (Bardanzellu et al, 2017;Li et al, 2020), goats (Sun et al, 2020), cattle (Nissen et al, 2017;Yamada et al, 2002) and pigs (Ferreira et al, 2021). In addition to these, although there are studies comparing colostrum or milk proteomes of different species in the literature (Akın et al, 2014;Li et al, 2021;Yang et al, 2017), there is no research on comparing the proteome profiles of high-quality and low-quality bovine colostrums. In light of this information, the aim of this study was to compare the proteomics of highand low-quality bovine colostrums for the first time.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the differences in proteomics of high‐quality bovine colostrum and low‐quality bovine colostrum

Kaçar,

Batmaz

2023

Veterinary Medicine & Sci

View full text Add to dashboard Cite

BackgroundAlthough there are studies on colostrum and milk proteomics of different species in the literature, there is no published report about different quality bovine colostrums’ proteomics.ObjectivesThe aim of this study was to compare the proteome content of high‐ and low‐quality bovine colostrums for the first time.MethodsColostrum samples were collected from 32 Holstein cows from the same farm that had just calved. Brix% levels of colostrums were measured, and then, those with a Brix% value of ≥27% were classified as high‐quality and those with a Brix% value of ˂22% as low‐quality. Three samples from high‐quality and low‐quality colostrums were selected and proteomic analyses were performed by pooling separately.ResultsTotally 95 proteins were identified in the colostrums, and 19 of them showed significant changes between high‐ and low‐quality colostrums. Expressions in colostrum of glycosylation‐dependent cell adhesion molecule‐1, cofilin‐1, alpha‐S2‐casein, alpha‐lactalbumin, alpha‐1B‐glycoprotein, actin_cytoplasmic‐1, nucleobindin‐1, cathelicidin‐4, inter‐alpha‐trypsin inhibitor heavy chain H4, chitinase‐3‐like protein 1 and monocyte differentiation antigen CD14 were lower, whereas tetranectin, secreted frizzled‐related protein‐1 (SFRP1), perilipin‐2, coatomer subunit epsilon (COPE), butyrophilin subfamily 1 member A1, polyubiquitin‐B, lactadherin and albumin levels were higher in high‐quality colostrum than low‐quality colostrum. Moreover, SFRP1, COPE and cathelicidin‐4 proteins were identified for the first time in bovine colostrum. In high‐quality colostrum, the most prominently down‐regulated proteins were cathelicidin‐4 (26.01‐fold) and cofilin‐1 (17.42‐fold), and the most prominently up‐regulated proteins were COPE (3.37‐fold) and tetranectin (3.07‐fold).ConclusionsIt was detected that the proteome contents of high‐ and low‐quality bovine colostrums were different from each other. As new functions are added to the protein databases regarding these proteins detected in colostrums, the interactions of proteins with each other and with other molecules will be detailed and the effects of high‐quality colostrums on passive transfer immunity and calf health will be understood in full detail.

show abstract

Novel insights into whey protein differences between donkey and bovine milk

Cited by 32 publications

References 37 publications

Proteomics and Peptidomics As a Tool to Compare the Proteins and Endogenous Peptides in Human, Cow, and Donkey Milk

Proteomics and Peptidomics As a Tool to Compare the Proteins and Endogenous Peptides in Human, Cow, and Donkey Milk

Physicochemical, structural, and emulsifying properties of stable blended whey and soy protein colloidal dispersion prepared by pH‐shifting and ultrasound

Evaluation of the differences in proteomics of high‐quality bovine colostrum and low‐quality bovine colostrum

Contact Info

Product

Resources

About