Novel method for the fabrication of ultrathin, free-standing and porous polymer membranes for retinal tissue engineering

Abstract

Retinal degeneration causes permanent visual loss and affects millions of people worldwide.

Highly porous Ce–W–TiO2 free-standing electrospun catalytic membranes for efficient de-NOxvia ammonia selective catalytic reduction

“…Free-standing porous membranes are strongly required for a wide of practical applications that include biomedical engineering, water treatment, air purification, and catalysis [1][2][3][4][5].…”

Hybrid three-dimensional (3D) bioprinting of retina equivalent for ocular research

“…Y79 cells express both cone-and rod-specific antigens [31][32][33] , and among ARPE-19 cells on the PCL membrane than that of a transwell membrane [16] . The ultrathin membrane is successfully utilized in this research to support ARPE-19 cell seeding, proliferation and formation of monolayer.…”

“…The bioprinting procedure was based on the drop-by-drop pattern to achieve a final seeding density of 2,786 ± 492 cells/cm 2 on an ultrathin membrane. The ultrathin membrane was fabricated according to our published protocol [16] . Then, the cells on the ultrathin membrane were further cultured for two weeks.…”

Retinal cell regeneration using tissue engineered polymeric scaffolds

“…Although TIPS allows the formation of a wellinterconnected polymer network, it does not allow for the adjustment of the pore size. It has been demonstrated that the ultrathin porous membrane, fabricated by separation phase, could act as a potential prosthetic BrM for RPE transplantation [99] . 3D printing Although conventional fabrication techniques have been widely used for scaffold preparation, they still lack fine control of structural aspects, such as the porosity, and scaffold dimensions and size.…”