Novel methodology for assessing biomaterial–biofluid interaction in cancellous bone

Bou-Francis, Antony; Soyka, René P. Widmer; Ferguson, Stephen J.; Hall, Richard M.; Kapur, Nikil

doi:10.1016/j.jmbbm.2015.02.027

Cited by 4 publications

(2 citation statements)

References 39 publications

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“…In fact, Jasper et al suggested that a higher modulus may translate to better mechanical stabilization, resulting in a lower use of Orthocomp™ compared to PMMA cement [55]. Similarly, for compressive yield strength and ultimate compressive strength, PMMA cements ranged from 50 ± 73 MPa and from 53 ± 80 MPa, respectively, but Orthocomp™ exhibited strength values 2–3 times those values [64]. …”

Section: Alternatives To Pmmamentioning

confidence: 99%

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

et al. 2016

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Percutaneous vertebroplasty procedure is of major importance, given the significantly increasing aging population and the higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving the injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main effects of PMMA bone cement on the heart, and the extent of influence of the materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case reports.

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Section: Alternatives To Pmmamentioning

confidence: 99%

A Review of PMMA Bone Cement and Intra‐Cardiac Embolism

et al. 2016

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show abstract

“…In fact, Jasper et al suggested higher modulus may translate to better mechanical stabilization resulting in less use of Orthocomp ™ compared to PMMA cement [55]. Similarly, for compressive yield strength and ultimate compressive strength, PMMA cements ranged from 50 ± 73 MPa and from 53 ± 80 MPa, respectively, but Orthocomp ™ exhibited strength values 2-3 times those values [64].…”

Section: Orthocomp ™ and Hydroxyapatitementioning

confidence: 99%

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Shridhar¹,

Chen²,

Khalil³

et al. 2016

Preprint

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Percutaneous vertebroplasty procedure is of major importance, given the significant increasing aging population and higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main features of PMMA bone cement on the heart, and the extent of influence of materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case report.

show abstract