2008
DOI: 10.1111/j.1439-0426.2007.01041.x
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Novel methods for assessing fish blood biochemical data

Abstract: SummaryThe purpose of this study was the identification and quantification of biochemical parameters over a 1-year cycle and to provide a detailed picture of seasonal changes in plasma metabolites and enzymes. Using the novel methods of machine learning techniques, the authors created and generated for the first time comprehensible classification models for exploring the importance of blood chemistry parameters, strength, mutual interactions or dependencies, and reliability of particular parameters within the … Show more

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Cited by 39 publications
(20 citation statements)
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“…() found correlations between plasma biochemical parameters and hepatic histopathological condition. Thus, plasma parameters are often regarded as suitable monitoring tools of the physiological status of the fish (Bowyer, Qin et al., ; Coz‐Rakovac et al., ; Díaz‐López et al., ; Kowalska et al., ) and could also be used as physiological indicators of lipogenesis affection with FO substitution (Richard et al., ). Under our experimental conditions, the inclusion of PO and LO did not affect plasma chemistry suggesting that fish were in acceptable nutritional status adding more evidences to the proper hepatic functioning even under FO absence.…”
Section: Discussionmentioning
confidence: 99%
“…() found correlations between plasma biochemical parameters and hepatic histopathological condition. Thus, plasma parameters are often regarded as suitable monitoring tools of the physiological status of the fish (Bowyer, Qin et al., ; Coz‐Rakovac et al., ; Díaz‐López et al., ; Kowalska et al., ) and could also be used as physiological indicators of lipogenesis affection with FO substitution (Richard et al., ). Under our experimental conditions, the inclusion of PO and LO did not affect plasma chemistry suggesting that fish were in acceptable nutritional status adding more evidences to the proper hepatic functioning even under FO absence.…”
Section: Discussionmentioning
confidence: 99%
“…Gill Na þ /K þ -ATPase activity inhibited significantly (p < 0.05) compared to control values at the end of acute exposure. Fish treated with silver nitrate exhibited hyponatremia, hypokalemia and hypochloremia, showed a percent decrease of 84.28%, 42.94% and 20.89%, respectively. Compared to control groups, fish after 96 h exposure had significantly (p < 0.05) higher plasma glucose and lower protein level.…”
Section: 2mentioning
confidence: 98%
“…The alterations of biochemical blood profile also used in the detection and diagnosis of metabolic disturbances and disease processes [42]. Among the biochemical parameters, plasma glucose and protein are widely used to assess the toxic stress [43].…”
Section: Introductionmentioning
confidence: 99%
“…Alanine transaminase (ALT) and aspartate aminotransferase (AST) enzymes are the most important aminotransferases related with amino acid metabolism in the liver of teleost fish (Coz-Rakovac et al, 2008). On the other hand, alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT) are important enzymes in the detection of the cell membrane of hepatocytes destruction (Kramer and Hoffmann, 1997).…”
Section: Discussionmentioning
confidence: 99%