Novel Mg-based alloys by selective laser melting for biomedical applications: microstructure evolution, microhardness and <i>in vitro</i> degradation behaviour

Long, Teng; Zhang, Xiaohong; Huang, Qianli; Liu, Ling; Liu, Yong; Ren, Junye; Yin, Yong; Wu, Dengke; Wu, Hong

doi:10.1080/17452759.2017.1411662

Cited by 58 publications

(41 citation statements)

References 34 publications

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“…Analysis of microstructure, layer-by-layer, showed major anisotropy of Young's modulus and modest anisotropy of other mechanical properties (Jhabvala et al 2010;Dadbakhsh, Hao, and Sewell 2012;Long et al 2018). This can be related to the irregular orientation of the grains in different directions.…”

Section: Introductionmentioning

confidence: 95%

A comprehensive study on variability of relative density in selective laser melting of Ti-6Al-4V

Khorasani

Gibson

Ghasemi

et al. 2019

Virtual and Physical Prototyping

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In this research, the effects of Selective Laser Melting (SLM) process parameters comprising laser power, scan speed, hatch space and scan pattern angle on the formation of porosity and subsequently density have been analysed. To improve the mechanical properties, post-processes (heat treatment) must be performed. Therefore, heat treatment was added to the design of experiment to analyse the effect of this process coupling with SLM process parameters on the value of density. A comprehensive design set with five levels for each parameter was selected so Taguchi L25 was used as the design of experiment. The significance of each parameter on obtained results was examined using statistical analysis (F-Test) and numerical model (interrogator analysis). The correlation between two process parameters was discussed by using 3D analytical and contour plots and the mechanisms behind these were discussed in depth. The contribution of this paper is a deep investigation of the relation of process parameters and heat treatment on density based on the Artificial Neural Network model. Results showed that better density is obtained with lower scan speed, laser power and scanning pattern angle. Meanwhile, for heat treatment and hatch space, the best density was obtained in their optimum range.

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Section: Introductionmentioning

confidence: 95%

A comprehensive study on variability of relative density in selective laser melting of Ti-6Al-4V

Khorasani

Gibson

Ghasemi

et al. 2019

Virtual and Physical Prototyping

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“…calvarial defect model, however the rate of resorption remained sufficiently high that voids were observed between the implant surface and mineralised bone after 84 days [191]. Magnesium alloys have been the most widely used resorbable alloys [192,193], and as a result a wide range have been processed by L-PBF, including pure Mg, WE43, AZ91 and several Mg-Zn alloys [167,189,190,[194][195][196][197][198][199][200]. When produced by conventional means, Mg alloys and particularly pure Mg show low tensile strength, of the order of 30 MPa when cast, requiring heat treatment as a result [192].…”

Section: Bioactive Alloysmentioning

confidence: 99%

Clinical, industrial, and research perspectives on powder bed fusion additively manufactured metal implants

Lowther

Louth

Davey

et al. 2019

Additive Manufacturing

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A B S T R A C TFor over ten years, metallic skeletal endoprostheses have been produced in select cases by additive manufacturing (AM) and increasing awareness is driving demand for wider access to the technology. This review brings together key stakeholder perspectives on the translation of AM research; clinical application, ongoing research in the field of powder bed fusion, and the current regulatory framework. The current clinical use of AM is assessed, both on a mass-manufactured scale and bespoke application for patient specific implants. To illuminate the benefits to clinicians, a case study on the provision of custom cranioplasty is provided based on prosthetist testimony. Current progress in research is discussed, with immediate gains to be made through increased design freedom described at both meso-and macro-scale, as well as long-term goals in alloy development including bioactive materials. In all cases, focus is given to specific clinical challenges such as stress shielding and osseointegration. Outstanding challenges in industrialisation of AM are openly raised, with possible solutions assessed. Finally, overarching context is given with a review of the regulatory framework involved in translating AM implants, with particular emphasis placed on customisation within an orthopaedic remit. A viable future for AM of metal implants is presented, and it is suggested that continuing collaboration between all stakeholders will enable acceleration of the translation process. fection or surgical complications [11][12][13].Currently, the majority of skeletal endoprostheses are produced from titanium (Ti) or cobalt chromium (CoCr) based alloys, which meet the criteria of durability, strength, corrosion resistance and a low immune response [14,15]. These characteristics however come at the cost of the high stiffness of these alloys in comparison to bone. Mismatch between the mechanical properties of bone and orthopaedic materials

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“…α-Mg, MgZn 2 , and Mg-Zn-Dy phases have been found to be distributed in the alloys with Dy. Alloys with Dy have significantly refined grain sizes [138]. Hardness monotonously increases with a decrease in grain size and an increase in second phase content.…”

Section: Laser-based Digital Microfabricationmentioning

confidence: 99%

“…The rate of mechanical integrity loss during degradation indicates the alloys' potential in bio-implant applications. A refined grain size, homogenous microstructure, and second phase content produced during SLM contribute to decreased degradation rates [138].…”

Section: Laser-based Digital Microfabricationmentioning

confidence: 99%

Review of materials used in laser-aided additive manufacturing processes to produce metallic products

et al. 2018

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Rapid prototyping (RP) or layered manufacturing (LM) technologies have been extensively used to manufacture prototypes composed mainly of plastics, polymers, paper, and wax due to the short product development time and low costs of these technologies. However, such technologies, with the exception of selective laser melting and sintering, are not used to fabricate metallic products because of the resulting poor life, short cycle, poor surface finish, and low structural integrity of the fabricated parts. The properties endowed by these parts do not match those of functional parts. Therefore, extensive research has been conducted to develop new additive manufacturing (AM) technologies by extending existing RP technologies. Several AM technologies have been developed for the fabrication of metallic objects. These technologies utilize materials, such as Ni-, Al-, and Ti-based alloys and stainless steel powders, to fabricate high-quality functional components. The present work reviews the type of materials used in laserbased AM processes for the manufacture of metallic products. The advantages and disadvantages of processes and different materials are summarized, and future research directions are discussed in the final section. This review can help experts select the ideal type of process or technology for the manufacturing of elements composed of a given alloy or material (Ni, Ti, Al, Pb, and stainless steel).

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Novel Mg-based alloys by selective laser melting for biomedical applications: microstructure evolution, microhardness and in vitro degradation behaviour

Cited by 58 publications

References 34 publications

A comprehensive study on variability of relative density in selective laser melting of Ti-6Al-4V

A comprehensive study on variability of relative density in selective laser melting of Ti-6Al-4V

Clinical, industrial, and research perspectives on powder bed fusion additively manufactured metal implants

Review of materials used in laser-aided additive manufacturing processes to produce metallic products

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