The success of the urban regeneration of an entire district, where the total or partial replacement of the building is planned because it is obsolete in terms of energy, seismic and social aspects, involves the balance between different requests. The process involves the demolition of old buildings still occupied and their replacement with a new sustainable building in turn supported by the construction of new equipped public spaces. The cost of these interventions should be covered by private capital. It is therefore essential the initiative of entrepreneurs who find economic convenience in the operation. Revenues are those expected from the sale of tradable surfaces (residences or other uses) obtained as volume premiums compared to the existing or as residual with respect to the amount returned to the old residents. In fact, the latter will have to accept a new equivalent residential surface lower than the existing property. The relationship between these two surfaces for each resident owner, the new one and the old one, should at least reflect the ratio of the corresponding market values. Another actor who can play a fundamental role in the success of the regeneration intervention is the public administration. The latter in view of the collective benefits deriving from urban regeneration on the entire district and on those adjacent to it (in which no intervention is planned), should implement a series of actions aimed at favoring the process. These include the aforementioned volumetric premiums, incentives for investors and residents in terms of tax exemption. This work aims, also through an application example, to implement a model able to define the balance between the different instances in order to manage the fundamental parameters that characterize the regeneration intervention and guarantee its success.