Novel narrow-band imaging magnifying endoscopic classification for early gastric cancer

Correlation between Magnifying Narrow-band Imaging Endoscopy Results and Organoid Differentiation Indicated by Cancer Cell Differentiation and its Distribution in Depressed-Type Early Gastric Carcinoma

“…Nakayoshi et al (2004) have demonstrated that the FNP is typical of differentiated-type carcinoma and the CSP is typical of undifferentiated-type carcinoma. Yokoyama et al (2010) also demonstrated that ILL-1 (CLP in this study) is related to differentiated adenocarcinoma. In this study, all cases with the CLP and the FNP were differentiated adenocarcinoma, and 18 of 19 cases with the CSP were undifferentiated adenocarcinoma.…”

“…Then, according Yokoyama et al (2010), the unclassified pattern lesions were further classified into lesions with papillary or granular micromucosal structures containing loop-like microvessels as chain loop pattern (CLP) and unclassified pattern. This CLP was first reported by Yokoyama et al (2010) as ILL-1. ILL-2 should be included in the unclassified lesions related to FNP and/or CSP.…”

Mucin phenotype and narrow-band imaging with magnifying endoscopy for differentiated-type mucosal gastric cancer

“…They have demonstrated that FNP is typical of differentiated-type carcinoma and a corkscrew pattern is typical of undifferentiated-type carcinoma. Yokoyama et al [3] have focused on morphological changes in the surface glandular structure of cancerous tissue, as well as the microvascular pattern. They have observed that differentiated-type carcinomas mainly demonstrate FNP and ILL, regardless of macroscopic appearance.…”

“…NBI-ME findings NBI-ME findings were classified as ILL or FNP, according to the microvascular architecture and microsurface structure [1,3]. ILL findings showed loop-like microvessels enclosed in papillary or granular structures (Fig.…”

“…Yokoyama et al have reported that differentiated-type carcinomas mainly exhibit an FNP or an intralobular loop pattern (ILL). ILL has a lobular surface structure that contains loop-like microvessels [3]. Therefore, the microvascular and surface glandular patterns of differentiated-type carcinomas can be classified into two main groups: FNP and ILL.…”