Novel Organization of the Staphylococcal Cassette Chromosome mec Composite Island in Clinical Staphylococcus haemolyticus and Staphylococcus hominis Subspecies hominis Isolates from Dogs

Abstract

In Thailand, the staphylococcal cassette chromosome mec (SCC mec ) element, which causes methicillin resistance through acquisition of the mec gene, has been studied in clinical coagulase-negative Staphylococcus isolates from various companion animals, and Staphylococcus haemolyticus and Staphylococcus hominis subsp. hominis were found to have the most nontypeable (NT)-SCC mec elements. These species are more prone to causing illness and more resistant to a variety of antimicrobials than other coagulase-negative staphylococci.

Comparative Genomic Analysis of a Multidrug-Resistant Staphylococcus hominis ShoR14 Clinical Isolate from Terengganu, Malaysia, Led to the Discovery of Novel Mobile Genetic Elements

“…A previous study had reported that 15 % (5/34 isolates) of S. hominis clinical isolates harbored SCCmec type VIII(4A), although that study had derived its conclusion from the PCR results of certain conserved regions of the SCCmec element [6]. A more recent study of S. hominis and S. haemolyticus isolates from dogs showed the presence of novel SCCmec composite islands, all of which were initially categorized as non-typeable SCCmec (NT-SCCmec) [28].…”