The research and design of low-noise imaging circuit is of great significance to enhance the imaging quality of the detector. To improve the imaging quality of an uncooled infrared imaging system, a low noise imaging circuit is designed. The generation scheme of bias voltage is emphasized, and the design methods of timing drive module and ADC conversion module are briefly described. A filter with a pass-band cutoff frequency of 1 Hz is designed at the bias voltage output to filter out high-frequency noise. The experimental results show that the precision of bias voltage is over 98% and the RMS noise of bias voltage below 1kHz is 1.4uV. The feasibility of other modules is verified by simulation and experiment.