Novel polystyryl resins for size exclusion chromatography

Abstract

New size exclusion chromatography (SEC) resins based on a crosslinker having independent vinyl groups have been produced and compared with SEC resins based on divinylbenzene‐55 (DVB). 1,2‐Bis(p‐vinylphenyl)ethane (p,p‐BVPE) and its meta‐isomers were suspension‐copolymerized with p‐methylstyrene in the presence of different porogens to give particles of about 5 μm average diameter. The porous particles were slurry‐packed into stainless steel columns for SEC evaluation. Calibration curves were obtained using narrow disperse polystyrene standards with molecular weights ranging from 580 to 3,040,000. The calibration curves for the new BVPE resins covered wider useful molecular weight ranges than those for comparable divinylbenzene resins. Particle size, surface morphology and the properties of pores were studied using a Coulter Multisizer II, scanning electron microscopy, nitrogen adsorption, and mercury porosimetry. © 1994 John Wiley & Sons, Inc.

Dispersion copolymerization of styrene and divinylbenzene. II. Effect of crosslinker on particle morphology

“…Li et al 27 recently reported the suspension copolymerization of p-methylstyrene with 1,2-bis(pvinylphenyl) ethane (and its m isomer); the vinyl sites of this crosslinker are deconjugated, unlike those of DVB. Spherical macroporous beads with a distinctive cauliflower surface texture were prepared, which compared very favorably with equivalent DVB-based resins as a packing material for size exclusion chromatography.…”

Fast, noninvasive and simultaneous near‐infrared spectroscopic characterisation of physicochemical stationary phases' properties: From silica particles towards monoliths

“…The protocol that can be found in the literature [41] was modified as follows: A mixture of 11.3 mL p-vinylbenzyl chloride (80 mmol) and 1.95 g magnesium (80 mmol) in 200 mL THF was gently stirred under argon at RT for 1.5 h. The rate of reaction was controlled by cooling with water or stirring. Afterwards, the mixture was extracted with a saturated NaCl solution.…”

Raspberry-like composite polymer particles by self-assemble heterocoagulation based on a charge compensation process

“…During the last two decades, the applications of the fine polymer particles have been gradually increasing in various fields, such as for electronic, biology, pharmacology, photographic industry, chromatography, controlled release reservoirs and chemical industry [1][2][3][4][5]. Recently, the possibility of utilization of heterocoagulation for the formation of polymer composite particles has been investigated by several groups [6][7][8] since it provides the possibility of better control for certain types of composite particle morphology.…”