2024
DOI: 10.1002/jhet.4808
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Novel 9H‐flouren containing indoline scaffolds: Synthesis, characterization, antimicrobial assays, and molecular docking study

Balraju Gangapuram,
Prakash Gupta Tanguturi,
Nisarg Gohil
et al.

Abstract: Abstract9H fluoren containing indoline scaffolds were developed by coupling indoline amine with α‐carboxylic acid group of amino acids in the presence of the peptide coupling reagent hexafluorophosphate benzotriazole tetramethyluronium (HBTU). All eight (12a–12h) synthesized indoline scaffolds were analyzed for their potent antibacterial and antifungal activities. The antibacterial assay revealed that compounds 12a, 12b, and 12e have shown excellent activity against pathogenic strains Pseudomonas aeruginosa, S… Show more

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