Novel spectrofluorimetric method for boldine alkaloid determination in herbal drugs and phytopharmaceuticals

Peralta, Cecilia; Henestrosa, Cecilia; Gil, Raúl A.; Fernández, Liliana Patricia; Acosta, Gimena

doi:10.1016/j.saa.2017.04.039

Cited by 6 publications

(3 citation statements)

References 25 publications

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“…Different parts of S. robusta such as leaves, stem bark, and floral parts were used for the various pharmacological activities. It stimulates the antioxidant, antibacterial, and wound healing and anti-inflammatory activity due to the presence of polyphenols, flavonoids, and triterpenoids [83,84]. These compounds are believed to be responsible for the pharmacological activities of plant extract.…”

Section: Resultsmentioning

confidence: 99%

Connection Approaches Between Traditional and Modern Pharmacological Profile of Shorea Robusta Gaertn. F.: A Review

Singh

Kumar

2018

Asian J Pharm Clin Res

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Shorea robusta is regarded as an important medicine in Ayurveda. S. robusta Gaertn. f. belongs to family Dipterocarpaceae, and traditionally, it is used to treat wounds, ulcers, leprosy, cough, gonorrhea, earache, and headache and many more. The use of different parts of this plant such as leaves, resin, and bark as a medicament for the treatment of various conditions is well documented in literature. It is the rich source of flavonoids, saponins, steroids, tannins, phenols, etc. mainly triterpenoids, which play the prominent role for their therapeutic potential in the drug. These compounds are believed to be responsible for the pharmacological activities of plant extract. The present review clarified the main active ingredients and pharmacological effects of S. robusta as a promising plant as a result of effectiveness and safety. Further studies should be carried out this plant to discover the unrevealed part of it which may serve for the welfare of humankind.

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Section: Resultsmentioning

confidence: 99%

Connection Approaches Between Traditional and Modern Pharmacological Profile of Shorea Robusta Gaertn. F.: A Review

Singh

Kumar

2018

Asian J Pharm Clin Res

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“…Therefore, its concentration and flow rate were optimized through multivariate experimental design. Furthermore, considering the results of some earlier works [14], the influence of the elution flow direction on the sensitivity and peak shape was studied. The best results were obtained when the elution was performed in a countercurrent manner (see Figure 2).…”

Section: Optimization Of Fia System and Flow Conditionsmentioning

confidence: 99%

“…Flow injection analysis (FIA) systems are recognized as excellent automated methods since they show advantages in terms of precision along with significant reduction in reagents and samples consumption, thus minimizing wastes and sampling times; unlike conventional batch mode. Furthermore, FIA schemes are easy to couple with different optical detectors [14] [15].…”

Section: Introductionmentioning

confidence: 99%

On-Line Photoinduced Fluorescence for Carbamazepine Determination after Multivariate Optimization

Henestrosa¹,

Peralta²,

Aragón³

et al. 2019

AJAC

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This work presents a simple and sensitive flow injection fluorimetric method for the determination of carbamazepine (CBZ) in pharmaceutical samples. It is based on the fluorescence signal measurement of the product generated by photoinduced (λ ex = 251 nm; λ em = 434 nm) using a flow injection manifold containing an on-line homemade photoreactor. In order to optimize the experimental setup, the variable conditions were studied using a multivariate optimization method, thus finding the set of optimum parameters according to the evaluated responses (sensitivity and sampling frequency) and minimizing the number of experiments performed. Under optimal experimental conditions, linear relationship with good correlation coefficient (0.9956) was found between the fluorescence intensity and CBZ concentration in the range of 0.13-40 µg•mL −1. The limit of detection was 0.04 µg•mL −1. The precision of the method was satisfactory; the values of relative standard deviations were better than 4.36%. The proposed method was validated and successfully applied to the determination of CBZ in pharmaceuticals with good accuracy; being the recovery values from 89.45%-112.20%.

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Boldine

Cassels

Castro-Saavedra

Fuentes-Barros

2021

A Centum of Valuable Plant Bioactives

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Novel spectrofluorimetric method for boldine alkaloid determination in herbal drugs and phytopharmaceuticals

Cited by 6 publications

References 25 publications

Connection Approaches Between Traditional and Modern Pharmacological Profile of Shorea Robusta Gaertn. F.: A Review

Connection Approaches Between Traditional and Modern Pharmacological Profile of Shorea Robusta Gaertn. F.: A Review

On-Line Photoinduced Fluorescence for Carbamazepine Determination after Multivariate Optimization

Boldine

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