Novel Swine-Origin (S-OIV) H1N1 Influenza A Pneumonia in a Lung Transplant Patient: A Case Report and Review of the Literature on Performance Characteristics of Rapid Screening Tests for the S-OIV

Challenges in the Diagnosis of 2009 H1N1 in a Lung Transplant Patient and the Long-Term Implications for Prevention and Treatment: A Case Report

“…In their recent study Raj et al outlined the utility of rRT-PCR as an expedient and highly sensitive means to identify H1N1 influenza 3. This has been confirmed by the Centers for Disease Control and Prevention, which indicated that the rRT-PCR assay is 99.3% sensitive for the 2009 H1N1 virus as compared to viral culture 16.…”

“…Subsequent reports on 2009 H1N1 in transplantation have highlighted the inconsistency of signs and symptoms at presentation, the necessity for early recognition and treatment, the potential for intensive care unit (ICU) admission and mechanical ventilation, and the risk for mortality 3–7. Yet these reports do not address the long-term impact of respiratory viral illnesses (RVIs) in lung transplantation, which have been associated with bronchiolitis obliterans syndrome (BOS) and death 8–10.…”

Fatal 2009 pandemic influenza A (H1N1) in a bone marrow transplant recipient

“…S-OIV infection has been reported in recipients of allogeneic hematopoietic cells [9][10][11], in addition to those who have undergone lung [20], kidney [21], heart [22,23] and liver transplantation [8]. Transplantation was included in the immunosuppressive conditions associated with S-OIV infection in fatal outcomes from California [6] and two fatal cases in Brazil [5].…”