Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy

Chen, Qiang; Huang, Xiaoyu; Zhang, Geyi; Li, Jiangnan; Liu, Yang; Xu, Yan

doi:10.1039/d2ra06631a

Cited by 17 publications

(2 citation statements)

References 72 publications

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“…Chen et al developed two species of prussian blue based-nanoparticles (PBNPs) having a metal–organic framework using cobalt (cobalt-iron) and copper (copper-iron) for the delivery of doxorubicin [ 110 ]. The cuboid NPs were then modified with polyethylene glycol methacylate (PEGMA) followed by attachment of the aptamer AS1411.…”

Section: Aptamer-modified Nanoconstructs In Cancer Therapymentioning

confidence: 99%

Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

Narwade¹,

Shaikh

Gajbhiye³

et al. 2023

Biomater Res

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The non-specificity of standard anticancer therapies has profound detrimental consequences in clinical treatment. Therapeutic specificity can be precisely achieved using cutting-edge ligands. Small synthetic oligonucleotide-ligands chosen through Systematic evolution of ligands by exponential enrichment (SELEX) would be an unceasing innovation in using nucleic acids as aptamers, frequently referred to as "chemical antibodies.” Aptamers act as externally controlled switching materials that can attach to various substrates, for example, membrane proteins or nucleic acid structures. Aptamers pose excellent specificity and affinity for target molecules and can be used as medicines to suppress tumor cell growth directly. The creation of aptamer-conjugated nanoconstructs has recently opened up innovative options in cancer therapy that are more effective and target tumor cells with minor toxicity to healthy tissues. This review focuses on a comprehensive description of the most capable classes of aptamer-tethered nanocarriers for precise recognition of cancer cells with significant development in proficiency, selectivity, and targetability for cancer therapy. Existing theranostic applications with the problems and future directions are also highlighted. Graphical Abstract

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Section: Aptamer-modified Nanoconstructs In Cancer Therapymentioning

confidence: 99%

Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

Narwade¹,

Shaikh

Gajbhiye³

et al. 2023

Biomater Res

View full text Add to dashboard Cite

show abstract

“…Cancer is one of the major causes of death globally. The most common type of cancer in women is breast cancer [ 1 ]. According to the 2020 annual report, 55.9 % of women are diagnosed with breast cancer, over the last 25 years, global trends in breast cancer incidence and mortality of 12.8 % indicate a remarkable rise worldwide [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

Platinum nanoparticles-embedded single-walled carbon nanotubes as a new carrier for curcumin delivery and investigating its anticancer effect on cell line 4T1

Mohammadi,

Bagheri,

Abutalebi

et al. 2024

Heliyon

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Catechol determination based on two dimensional SnSe nanosheets modified glassy carbon electrode with enhanced sensitivity

Mohammadzadeh Jahani,

Tajik

2024

J Mater Sci: Mater Electron

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Novel targeted pH-responsive drug delivery systems based on PEGMA-modified bimetallic Prussian blue analogs for breast cancer chemotherapy

Abstract: Core–shell structured bimetallic PBA@PEGMA@AS1411-based DOX loading and pH-responsive controlled release systems for breast cancer chemotherapy.

Cited by 17 publications

References 72 publications

Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery

Platinum nanoparticles-embedded single-walled carbon nanotubes as a new carrier for curcumin delivery and investigating its anticancer effect on cell line 4T1

Catechol determination based on two dimensional SnSe nanosheets modified glassy carbon electrode with enhanced sensitivity

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