Novel transformations of 1H-isothiochromen-4(3H)-one 2,2-dioxide

Tkachuk, T. M.; Shyshkina, Olena O.; Volovnenko, T. A.; Volovenko, Yulian M.; Zubatyuk, Roman I.; Medviediev, Volodymyr V.; Шишкин, Олег В.

doi:10.1007/s00706-012-0858-6

Cited by 8 publications

References 10 publications

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ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

et al. 2013

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Novel Transformations of 1H-Isothiochromen-4(3H)-one 2,2-Dioxide. -Compound (III) prepared from (I) by the reaction with dimethylformamide dimethylacetal reacts with some nitrogen nucleophiles. Vilsmeyer-Haack reaction with dimethylformamide results in the formation of (VI) which is unstable and decomposes quickly, but its structure is elucidated by X-ray. Further X-ray structures are given for (III),, (X), (XIIb), and (XIId). -(TKACHUK, T.; SHYSHKINA*, O. O.; VOLOVNENKO, T. A.; VOLOVENKO, Y. M.; ZUBATYUK, R. I.; MEDVIEDIEV, V. V.; SHISHKIN, O. V.; Monatsh. Chem. 144 (2013) 2, 263-271, http://dx.doi.org/10.1007/s00706-012-0858-6 ; Dep. Chem., Taras Shevchenko Kiev. Natl. Univ., Kiev 01033, Ukraine; Eng.) -M. Bohle 24-130

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ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

et al. 2013

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Synthesis of 4,4‐Disubstituted 1,2‐Thiazinane‐5‐one 1,1‐Dioxides via the CSIC^[≠]Reaction Strategy

et al. 2020

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A series of sp3‐enriched 2,2‐disubstituted 1,2‐thiazinane‐5‐one 1,1‐dioxides (including spirocyclic derivatives) has been synthesized through the CSIC [Carbanion mediated Sulfonate (Sulfonamido) Intramolecular Cyclization] reaction strategy. In particular, 2,2‐disubstituted alkyl 3‐aminopropanoates were subsequently sulfonylated with mesyl chloride followed by alkylation with methyl iodide to give the key precursor 2,2‐disubstituted methyl 3‐(methylsulfonamido)propanoates. The latter were treated with sodium hydride and underwent the intramolecular sulfa‐Dieckmann cyclization yielding the target 4,4‐disubstituted 1,2‐thiazinane‐5‐one 1,1‐dioxides (so‐called β‐keto‐δ‐sultams). The structure of the target compounds was confirmed by an X‐ray diffraction study.

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The reactivity of tetrahydropyrrolo[1,2-b]isothiazol-3(2H)-one 1,1-dioxides

et al. 2020

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Novel transformations of 1H-isothiochromen-4(3H)-one 2,2-dioxide

Cited by 8 publications

References 10 publications

ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

Synthesis of 4,4‐Disubstituted 1,2‐Thiazinane‐5‐one 1,1‐Dioxides via the CSIC^[≠]Reaction Strategy

The reactivity of tetrahydropyrrolo[1,2-b]isothiazol-3(2H)-one 1,1-dioxides

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Novel transformations of 1H-isothiochromen-4(3H)-one 2,2-dioxide

Cited by 8 publications

References 10 publications

ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

ChemInform Abstract: Novel Transformations of 1H‐Isothiochromen‐4(3H)‐one 2,2‐Dioxide.

Synthesis of 4,4‐Disubstituted 1,2‐Thiazinane‐5‐one 1,1‐Dioxides via the CSIC[≠]Reaction Strategy

The reactivity of tetrahydropyrrolo[1,2-b]isothiazol-3(2H)-one 1,1-dioxides

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Synthesis of 4,4‐Disubstituted 1,2‐Thiazinane‐5‐one 1,1‐Dioxides via the CSIC^[≠]Reaction Strategy