Novel Treatment Paradigms: Primary IgA Nephropathy

Selvaskandan, Haresh; Barratt, Jonathan; Cheung, Chee Kay

doi:10.1016/j.ekir.2023.11.026

Kidney International Reports

2024

DOI: 10.1016/j.ekir.2023.11.026

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Novel Treatment Paradigms: Primary IgA Nephropathy

Haresh Selvaskandan,

Jonathan Barratt,

Chee Kay Cheung

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2024

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Cited by 15 publications

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IPNA clinical practice recommendations for the diagnosis and management of children with IgA nephropathy and IgA vasculitis nephritis

Vivarelli,

Samuel,

Coppo

et al. 2024

Pediatr Nephrol

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IgA nephropathy and IgA vasculitis with nephritis, albeit rare, represent two relatively frequent glomerular conditions in childhood. Compared to adults, pediatric IgA nephropathy has a more acute presentation, most frequently with synpharyngitic macrohematuria and histologically with more intense inflammation and less intense chronic damage. Management of these conditions is controversial and supported by little high-quality evidence. The paucity of evidence is due to the disease heterogeneity, its inter-ethnic variability, and the difficulty of extrapolating data from adult studies due to the peculiarities of the condition in children. IgA vasculitis with nephritis is a kidney manifestation of a systemic disorder, typical of the pediatric age, in which both the diagnosis of kidney involvement and its management are poorly defined, and an interdisciplinary approach is crucial. Both conditions can have a profound and long-lasting impact on kidney function and the global health of affected children. The International Pediatric Nephrology Association has therefore convened a diverse international group of experts from different disciplines to provide guidance on the recommended management of these conditions in children and to establish common definitions and define priorities for future high-quality, evidence-based collaborative studies for the benefit of children.

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IPNA clinical practice recommendations for the diagnosis and management of children with IgA nephropathy and IgA vasculitis nephritis

Vivarelli,

Samuel,

Coppo

et al. 2024

Pediatr Nephrol

View full text Add to dashboard Cite

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Urinary Soluble CD163: A Novel Biomarker Suggests Who Should Receive Glucocorticoids in IgA Nephropathy

Li,

Thanabalasingam

2024

Kidney International Reports

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Recent status and trends of innate immunity and the gut-kidney aixs in IgAN: A systematic review and bibliometric analysis

Li,

et al. 2024

International Immunopharmacology

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Novel Treatment Paradigms: Primary IgA Nephropathy

Cited by 15 publications

References 71 publications

IPNA clinical practice recommendations for the diagnosis and management of children with IgA nephropathy and IgA vasculitis nephritis

IPNA clinical practice recommendations for the diagnosis and management of children with IgA nephropathy and IgA vasculitis nephritis

Urinary Soluble CD163: A Novel Biomarker Suggests Who Should Receive Glucocorticoids in IgA Nephropathy

Recent status and trends of innate immunity and the gut-kidney aixs in IgAN: A systematic review and bibliometric analysis

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