Novel Ventricular Repolarization Indices in Patients with Coronary Slow Flow

Sucu, Murat; Uçaman, Berzal; Özer, Orhan; Altaş, Yakup; Polat, Esra

doi:10.4022/jafib.1446

Cited by 8 publications

(9 citation statements)

References 24 publications

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“…On the other hand, reports concerning the status of corrected QT interval (QTc) are conflicting. Sucu et al [8] and Atak et al [29] reported similar QTc interval between patients exhibiting CSFP and those with normal flow, whereas Karaman et al [10] and Sezgin et al [30] demonstrated a significant escalation in mean QTc in CSFP patients compared with those of normal coronary flow. However, Atak et al [29] further reported an increase in the dispersion of QTc (QTcd) in their study despite similar maximum-QTc intervals.…”

Section: Discussionmentioning

confidence: 96%

“…There are a number of studies conducted with specific ECG markers for the anticipation of sudden death in patients with CSFP. Recent evidence suggested that some ECG parameters of ventricular repolarization such as Tp-e interval, QTd, and Tp-e/QT and Tp-e/QTc ratios were increased in the setting of CSFP [8][9][10]. Additionally, Yilmaz et al [28] demonstrated a significant association between CSFP and QRS fragmentation.…”

Section: Discussionmentioning

confidence: 99%

“…Previous evidence concerning the effect of CSFP on electrocardiographic (ECG) indices showed that the P wave dispersion and the parameters of ventricular repolarization, such as Tpeak-to-Tend interval (Tp-e), QT dispersion (QTd), T wave, Jpoint-to-Twave interval, and Tp-e/QT and Tp-e/QTc ratios, were significantly greater in patients with CSFP than the subjects with normal coronary flow [6,[8][9][10]. In addition, these parameters are known to associate with the atrial and ventricular tachyarrhythmia generation.…”

Section: Introductionmentioning

confidence: 99%

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Relationship between frontal QRS-T angle and coronary slow flow phenomenon

Özbek¹

2021

Journal of Surgery and Medicine

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Relationship between frontal QRS-T angle and coronary slow flow phenomenon

Özbek¹

2021

Journal of Surgery and Medicine

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“…have demonstrated that repolarization markers were significantly increased in vasospastic angina patients with malignant arrhythmic events than those without (32). Also, Sucu et al have reported that coronary slow flow was associated with prolonged duration of repolarization parameters and possible association with ventricular arrhythmias (33). In various patient populations such as patients with coronary artery ectasia (34,35), stable CAD with coronary collateral circulation (36), patients treated with reperfusion methods (19,37), these electrocardiographic repolarization markers have been found to be more prolonged than control patients.…”

Section: Discussionmentioning

confidence: 98%

Repolarization Parameters in Patients with Premature Coronary Artery Disease

Ekizler¹,

Tak²,

Çay³

et al. 2019

atfm

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Amaç: Genç bireylerde koroner arter hastalığı nispeten nadir görülür. Literatürde genç yaşta koroner arter hastalığı ile ilgili sınırlı veri mevcuttur. Bu çalışmada yeni tanı almış prematür koroner arter hastalığı olanlarda repolarizasyon parametreleri değerlendirildi. Gereç ve Yöntem: Çalışmaya toplam 200 hasta [128 erkek, 38,0 (29,3-42,0) yaş] dahil edildi ve bunlardan 100'ü yeni tanı prematür koroner arter hastalığı (yaş ≤45) olan çalışma grubunu oluşturdu. Kalan 100 hasta iyi eşleştirilmiş kontrol grubunu oluşturdu. İki grup arasında DII, V2 ve V6 derivasyonlarında ölçülen, QTc intervali, Tp-e intervali ve Tp-e∕QTc den oluşan repolarizasyon parametreleri karşılaştırıldı. Bulgular: Median QTc intervali D2 derivasyonunda (430,3 ms ve 405,3 ms, p<0,001),V2 derivasyonunda (433,8 ms ve 404,7 ms, p<0,001) V6 derivasyonunda (430,2 ms ve 401,7 ms, p<0,001); median Tp-e intervali D2 derivasyonunda (80 ms ve 64 ms, p<0,001), V2 derivasyonunda (82 ms ve 74 ms, p<0,001), V6 derivasyonunda (88 ms ve 72 ms, p<0,001); ve median Tp-e/QTc oranı; D2 derivasyonunda (0,188 ve 0,158, p<0,001), V2 derivasyonunda (0,190 ve 0,181, p=0,022) ve V6 derivasyonunda (0,196 ve 0,183, p<0,001) olmak üzere sırasıyla prematür koroner arter hastalığı olanlarda kontrol grubuna göre anlamlı olarak daha yüksek saptandı. Sonuç: Sonuç olarak, prematür koroner arter hastalığı anormal repolarizasyon dispersiyonu ve dolayısıyla aritmik risk ile ilişkili olabilir.Objectives: Coronary artery disease (CAD) in young adults is relatively rare. Few data on CAD in young adults are available in the literature. In the current study, repolarization parameters were evaluated in patients with newly diagnosed premature CAD. Materials and Methods: A total of 200 patients [128 male, 38.0 (29.3-42.0) years] were included and 100 cases with newly diagnosed premature coronary heart disease (aged ≤45 years) formed the study group. Remaining 100 cases were well-matched controls. Repolarization parameters including QTc interval, Tp-e interval and Tp-e∕QTc in leads DII, V2 and V6 were compared between the two groups. Results: The median QTc interval (430.3 ms vs 405.3 ms, p<0.001) in lead D2, (433.8 ms vs 404.7 ms, p<0.001) in lead V2 and (430.2 ms vs 401.7 ms, p<0.001) in lead V6; the median Tp-e interval (80 ms vs 64 ms, p<0.001) in lead D2, (82 ms vs 74 ms, p<0.001) in lead V2 and (88 ms vs 72 ms, p<0.001) in lead V6; and the median Tp-e/QTc (0.188 vs 0.158, p<0.001) in lead D2, (0.190 vs 0.181, p=0.022) in lead V2 and (0.196 vs 0.183, p<0.001) in lead V6 were significantly higher in patients with premature CAD compared controls, respectively. Conclusion: In conclusion, premature coronary heart disease may be related to abnormal dispersion of repolarization and subsequent arrhythmic risk.

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“…In some cases, indices characterizing duration and morphology of action potentials (QT, JTpeak and JTend intervals)[ 117 - 120 ], as well as electrical instability of ventricular myocardium at cellular level (macrovolt and microvolt T-wave alternans, beat-to-beat T-vector variability)[ 121 , 122 ] may be of clinical importance (Table 1 ).…”

Section: Other Repolarization Parametersmentioning

confidence: 99%

Dispersion of ventricular repolarization: Temporal and spatial

Arteyeva¹

2020

WJC

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Repolarization heterogeneity (RH) is an intrinsic property of ventricular myocardium and the reason for T-wave formation on electrocardiogram (ECG). Exceeding the physiologically based RH level is associated with appearance of life-threatening ventricular arrhythmias and sudden cardiac death. In this regard, an accurate and comprehensive evaluation of the degree of RH parameters is of importance for assessment of heart state and arrhythmic risk. This review is devoted to comprehensive consideration of RH phenomena in terms of electrophysiological processes underlying RH, cardiac electric field formation during ventricular repolarization, as well as clinical significance of RH and its reflection on ECG parameters. The formation of transmural, apicobasal, left-to-right and anterior-posterior gradients of action potential durations and end of repolarization times resulting from the heterogenous distribution of repolarizing ion currents and action potential morphology throughout the heart ventricles, and the different sensitivity of myocardial cells in different ventricular regions to the action of pharmacological agents, temperature, frequency of stimulation, etc ., are being discussed. The review is focused on the fact that RH has different aspects – temporal and spatial, global and local; ECG reflection of various RH aspects and their clinical significance are being discussed. Strategies for comprehensive assessment of ventricular RH using different ECG indices reflecting various RH aspects are presented.

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Novel Ventricular Repolarization Indices in Patients with Coronary Slow Flow

Cited by 8 publications

References 24 publications

Relationship between frontal QRS-T angle and coronary slow flow phenomenon

Relationship between frontal QRS-T angle and coronary slow flow phenomenon

Repolarization Parameters in Patients with Premature Coronary Artery Disease

Dispersion of ventricular repolarization: Temporal and spatial

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