Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders

Kiran, Neelakanta Sarvashiva; Yashaswini, Chandrashekar; Chatterjee, Ankita

doi:10.1016/j.lfs.2023.122311

Life Sciences

2024

DOI: 10.1016/j.lfs.2023.122311

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Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders

Neelakanta Sarvashiva Kiran,

Chandrashekar Yashaswini,

Ankita Chatterjee

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2024

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Cited by 3 publications

References 152 publications

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Paraben preservatives exhibit inhibition on human and rat steroid 5α-reductase 1: A comprehensive 3D-QSAR and computational analysis

Zhu,

Ding,

Tang

et al. 2024

Journal of Hazardous Materials

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Paraben preservatives exhibit inhibition on human and rat steroid 5α-reductase 1: A comprehensive 3D-QSAR and computational analysis

Zhu,

Ding,

Tang

et al. 2024

Journal of Hazardous Materials

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One dimensional multilayer structure for kerosene adulteration detection in petrol and diesel

Monika,

Prakash

2024

Eng. Res. Express

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We aim to design a multilayer periodic structure to detect the kerosene adulteration in the petrol and diesel fuels on a single processing setup. We built the structure by arranging TiO2 and SiO2 layers periodically in alternate manner with empty space at the middle. The optical response of the designed structure is then theoretically studied using transfer matrix method. Empty space of the design is filled with different kerosene adulterated petrol and diesel samples for inspecting structure response to incident electromagnetic waves. Theoretical calculations affirm that the proposed structure is capable to detect the fuel adulteration efficiently. Critical performance parameters like sensitivity, quality factor, figure of merit and limit of detection are calculated to check the effectiveness of the sensor. We also optimized the sensitivity of sensors design through modifying the defect thickness as well as angle of incidence of electromagnetic waves, and provides poly fit formula. It is observed that the sensitivity of sensor to detect kerosene adulteration in fuels highly depends on defect thickness and light incidence angle. An efficient sensor possessing high quality factor and figure of merit is realized from the designed structure that is capable of detecting 10^(-5) RIU.

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Use of Cosmetics in Pregnancy and Neurotoxicity: Can It Increase the Risk of Congenital Enteric Neuropathies?

Jones,

Wessel,

Schäfer

et al. 2024

Biomolecules

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Pregnancy is a particularly vulnerable period for the growing fetus, when exposure to toxic agents, especially in the early phases, can decisively harm embryo development and compromise the future health of the newborn. The inclusion of various chemical substances in personal care products (PCPs) and cosmetic formulations can be associated with disruption and damage to the nervous system. Microplastics, benzophenones, parabens, phthalates and metals are among the most common chemical substances found in cosmetics that have been shown to induce neurotoxic mechanisms. Although cosmetic neurotoxin exposure is believed to be minimal, different exposure scenarios of cosmetics suggest that these neurotoxins remain a threat. Special attention should be paid to early exposure in the first weeks of gestation, when critical processes, like the migration and proliferation of the neural crest derived cells, start to form the ENS. Importantly, cosmetic neurotoxins can cross the placental barrier and affect the future embryo, but they are also secreted in breast milk, so babies remain exposed for longer periods, even after birth. In this review, we explore how neurotoxins contained in cosmetics and PCPs may have a role in the pathogenesis of various neurodevelopmental disorders and neurodegenerative diseases and, therefore, also in congenital enteric aganglionosis as well as in postnatal motility disorders. Understanding the mechanisms of these chemicals used in cosmetic formulations and their role in neurotoxicity is crucial to determining the safety of use for cosmetic products during pregnancy.

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Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders

Cited by 3 publications

References 152 publications

Paraben preservatives exhibit inhibition on human and rat steroid 5α-reductase 1: A comprehensive 3D-QSAR and computational analysis

Paraben preservatives exhibit inhibition on human and rat steroid 5α-reductase 1: A comprehensive 3D-QSAR and computational analysis

One dimensional multilayer structure for kerosene adulteration detection in petrol and diesel

Use of Cosmetics in Pregnancy and Neurotoxicity: Can It Increase the Risk of Congenital Enteric Neuropathies?

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