NR-WS-37 Arterial spin labeling et perfusion de 1er passage : etude comparee dans les AVC

Monet, P.; Franc, J.; Sankari, S. Stoquar-El; Balédent, Olivier; Perrin, M.; Brochart, C.; Blanpain, S.; Deramond, H.; Lehmann, P.

doi:10.1016/s0221-0363(08)76896-3

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“…For example, PASL was used to measure absolute blood flow changes in different regions of the brain in response to stimuli such as ingestion of different simple sugars; thus, there is differential stimulation of hypothalamic regions with glucose and fructose. [39][40][41] This approach has the potential to understand the activation of anatomical regions of the hypothalamus in response to nutrients during postprandial satiation.…”

Section: Targeting the Central Nervous System In Obesity Treatmentmentioning

confidence: 99%

Recent advances in clinical practice challenges and opportunities in the management of obesity

Acosta

Dayyeh

Port

et al. 2014

Gut

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Despite advances in understanding the roles of adiposity, food intake, gastrointestinal and adipocyte-related hormones, inflammatory mediators, the gut-brain axis, and the hypothalamic nervous system in the pathophysiology of obesity, the effects of different therapeutic interventions on those pathophysiological mechanisms are controversial. There are still no low cost, safe, effective treatments for obesity and its complications. Currently, bariatric surgical approaches targeting the gastrointestinal tract are more effective than non-surgical approaches in inducing weight reduction and resolving obesity-related comorbidities. However, current guidelines emphasize non-surgical approaches through life-style modification and medications to achieve slow weight loss, which is not usually sustained and may be associated with medication-related side effects. This review analyzes current central, peripheral, or hormonal targets to treat obesity, and addresses challenges and opportunities to develop novel approaches for obesity.

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Section: Targeting the Central Nervous System In Obesity Treatmentmentioning

confidence: 99%

Recent advances in clinical practice challenges and opportunities in the management of obesity

Acosta

Dayyeh

Port

et al. 2014

Gut

View full text Add to dashboard Cite

show abstract

NR-WS-37 Arterial spin labeling et perfusion de 1er passage : etude comparee dans les AVC

Cited by 1 publication

References 0 publications

Recent advances in clinical practice challenges and opportunities in the management of obesity

Recent advances in clinical practice challenges and opportunities in the management of obesity

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