The effects of niobium and oxygen content on the mechanical properties, phase stability and elastic deformation behavior of Ti-Nb-Ta-Zr-O alloys were investigated by employing tensile tests, microstructure observations and XRD analysis. The basic composition of the tested alloys used was Ti-36%Nb-2%Ta-3%Zr-0.3%O (mass%), with the other alloys having lower niobium content (from 32% to 36%) and higher oxygen content (0.5%). Orthorhombic 00 was observed in the specimens with lower niobium content. Work hardening and elastic deformation behavior in the specimens with lower niobium (33% to 34%) and higher oxygen (0.5%) contents are similar to those of the alloy with basic composition; these specimens showed little work hardening and non-linearity in the elastic range of tensile deformation. The phase configuration analysis of these specimen alloys does not show the presence of any peaks other than the phase before and after cold working. The cold worked Ti-32%Nb-2%Ta-3%Zr-0.5%O has a Young's modulus of 55 GPa, a tensile strength of 1370 MPa and a tensile elongation of 12%. After heat treatment at 623 K for 600 s, the tensile strength of the alloy reaches 1500 MPa, with a Young's modulus of 58 GPa and a tensile elongation of 10%. [