Nrf2 protects against renal fibrosis induced by chronic cadmium exposure in mice

Chen, Chengjie; Zhou, Zhengsheng; Yu, Shudong; Ma, Yawei; Wang, Gang; Han, Xue; Jiao, Congcong; Luan, Junjun; Liu, Zhiyuan; Xu, Yuanyuan; Zhang, Qiang; Fu, Jingqi; Zhou, Hua; Pi, Jingbo

doi:10.1016/j.fct.2023.113875

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Cited by 5 publications

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“… 47 On one hand, Nrf2 -KO mice have been found to be vulnerable to Cd-induced kidney damage. 48 , 49 On the other hand, exogenous NRF2 activators protect against Cd-induced hepatotoxicity and nephrotoxicity. 50 , 51 In addition, NRF2 and L-NRF1 have been reported to transcriptionally regulate the expression of metallothionein (MT), 52 , 53 which is a cysteine-rich protein involved in Cd detoxification and transportation.…”

Section: Discussionmentioning

confidence: 99%