NT-pro-BNP, but not C-reactive protein, is predictive of atrial fibrillation in patients undergoing coronary artery bypass surgery

Abstract

Preoperative and postoperative NT-pro-BNP as well as TnT values were significantly higher in patients who subsequently developed AF. TCLG and CRP were not useful in identifying patients at higher risk for AF. Multivariate analysis identified age, preoperative NT-pro-BNP and duration of CPB as independent correlates of AF.

Preoperative High N-Terminal pro-B-Type Natriuretic Peptide Level Can Predict the Incidence of Postoperative Atrial Fibrillation Following Off-Pump Coronary Artery Bypass Grafting

“…They concluded that preoperative NT-pro-BNP, duration of cardiopulmonary bypass and advanced age were the independent predictors. 34 Iskesen I, et al reported the same situation and concluded the positive correlation between high levels of preoperative NT-pro-BNP and risk of new-onset AF after conventional CABG. 35 Kerbaul F reported that preoperative and postoperative NT-pro-BNP levels after OPCAB could predict cardiovascular complications.…”

Postoperative Atrial Fibrillation Is Associated With High On-Aspirin Platelet Reactivity

“…Significant associations between dense spontaneous echo contrast and the 2 indexes, Creactive protein and soluble P-selection, support the hypothesis of increased inflammatory activity for thrombogenesis in AF (5). Inflammatory markers play an important role in the development of AF, although the results are not consistent (3). An association of preoperative platelet activity and POAF has been shown previously (21,22).…”

“…Due to the lack of data describing the time point when POAF occurred after CABG in our analysis, one could argue against our hypothesis of an association between POAF and HAPR. When analyzing the available data on the time association of POAF and open-heart surgery, most reports indicate the highest incidence within the first 4 days following the procedure, peaking around the second day (3,20). Therefore, if the timing of postoperative PFT was synchronized with the timing of POAF, the association effect of POAF and HAPR could only have been stronger.…”

“…In spite of all the prophylactic measures, postoperative atrial fibrillation (POAF) still occurs in about 15-30% of coronary artery bypass grafting (CABG) patients (1)(2)(3)(4). It is associated with increased riskadjusted mortality, hospital costs, and readmission rates (4) as well as late mortality (1,2).…”

Where is the ruptured bronchial artery aneurysm?☆

“…I am very glad to see that Dr Shih et al reported my case of haemomediastinum caused by a ruptured bronchial artery aneurysm [1]. This is one of the bronchial arterial embolisation cases that I performed during October 2006.…”