Nuclear cataract ‐ a microradiographic study

Palmquist, B. M.; Philipson, Bo

doi:10.1111/j.1755-3768.1988.tb04060.x

Cited by 11 publications

(6 citation statements)

References 12 publications

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“…Cells located in the center of the lens have significantly higher protein contents than those situated near the surface. 25 Paralleling this protein gradient is a refractive index gradient 26 that serves to correct longitudinal spherical aberration. Despite its central importance to the optics of the eye, little is known about how the refractive index gradient is generated in the lens and adjusted over the lifespan to match the refractive needs of the animal.…”

Section: Discussionmentioning

confidence: 99%

A Role forEpha2in Cell Migration and Refractive Organization of the Ocular Lens

Shi

María

Bennett

et al. 2012

Invest. Ophthalmol. Vis. Sci.

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Section: Discussionmentioning

confidence: 99%

A Role forEpha2in Cell Migration and Refractive Organization of the Ocular Lens

Shi

María

Bennett

et al. 2012

Invest. Ophthalmol. Vis. Sci.

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“…Older studies have suggested that light toxicity, oxidation of lens proteins, use of intraocular gas, and length of operative time may be causative factors (Cherfan 1991; de Bustros 1988; Ogura 1991). Newer research suggests that vitrectomy surgery increases oxygen tension within the eye; oxygen exposure has been linked with progressive nuclear sclerotic cataract formation (Holekamp 2005; Palmquist 1988). …”

Section: Introductionmentioning

confidence: 99%

Surgery for post-vitrectomy cataract

Diana

Gichuhi

Vedula

et al. 2013

Cochrane Database of Systematic Reviews

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Background Cataract formation or acceleration can occur after intraocular surgery, especially following vitrectomy, a surgical technique for removing the vitreous which is used in the treatment of disorders that affect the posterior segment of the eye. The underlying problem that led to vitrectomy may limit the benefit from cataract surgery. Objectives The objective of this review was to evaluate the effectiveness and safety of surgery for post-vitrectomy cataract with respect to visual acuity, quality of life, and other outcomes. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 4), Ovid MEDLINE, Ovid MEDLINE in-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily Update, Ovid OLDMED-LINE (January 1946 to May 2013), EMBASE (January 1980 to May 2013, Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to May 2013), PubMed (January 1946 to May 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrial.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 22 May 2013. Selection criteria We planned to include randomized and quasi-randomized controlled trials comparing cataract surgery with no surgery in adult patients who developed cataract following vitrectomy. Data collection and analysis Two authors screened the search results independently according to the standard methodological procedures expected by The Cochrane Collaboration. Main results We found no randomized or quasi-randomized controlled trials comparing cataract surgery with no cataract surgery for patients who developed cataracts following vitrectomy surgery. Authors' conclusions There is no evidence from randomized or quasi-randomized controlled trials on which to base clinical recommendations for surgery for post-vitrectomy cataract. There is a clear need for randomized controlled trials to address this evidence gap. Such trials should stratify participants by their age, the retinal disorder leading to vitrectomy, and the status of the underlying disease process in the contralateral eye. Outcomes assessed in such trials may include gain of vision on the Early Treatment Diabetic Retinopathy Study (ETDRS) scale, quality of life, and adverse events such as posterior capsular rupture. Both short-term (six-month) and long-term (one-year or two-year) outcomes should be examined.

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“…Previous research suggests that underlying reasons might include light toxicity, excessive oxygenation of lens proteins, gas endotamponade and prolonged time of surgery [1][2][3][4]. Many studies suggest that PPV may contribute to increased intraocular oxygen pressure and that oxygen exposure leads to progressive cataract formation [5,6].…”

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confidence: 99%

Lens opacities after pars plana vitrectomy with intraocular SF6 gas tamponade

Górska¹,

Sirek²,

Jastrzębska-Miazga³

et al. 2023

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Pars plana vitrectomy (PPV) allows the treatment of many vitreous, retina or choroid disorders. Over time PPV has become widely used in the treatment of many eye pathologies such as vitreous haemorrhage, macular hole, epiretinal membrane and vitreomacular traction syndrome.However, due to the many potential complications, close monitoring of the patient's condition is required during the early and late postoperative period. Those complications may include e.g. endophthalmitis, increased intraocular pressure, retinal detachment, maculopathy and cataract. The development of a nuclear cataract or its progression is considered to be the most common late complication of vitrectomy. The exact pathogenesis of cataract formation or opacity progression following vitrectomy is unknown. Previous research suggests that underlying reasons might include light toxicity, excessive oxygenation of lens proteins, gas endotamponade and prolonged time of surgery [1][2][3][4]. Many studies suggest that PPV may contribute to increased intraocular oxygen pressure and that oxygen exposure leads to progressive cataract formation [5,6]. MaTeRIal aND MeThODsThis study included 19 patients (12 women and 7 men; mean age 65 ±8.4 years) who underwent PPV with intraocular SF6 gas tamponade before cataract phacoemulsification.

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Nuclear cataract ‐ a microradiographic study

Cited by 11 publications

References 12 publications

A Role forEpha2in Cell Migration and Refractive Organization of the Ocular Lens

A Role forEpha2in Cell Migration and Refractive Organization of the Ocular Lens

Surgery for post-vitrectomy cataract

Lens opacities after pars plana vitrectomy with intraocular SF6 gas tamponade

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