Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry-Based Metabolomics for Cancer Diagnosis

Metabolomic studies of breast cancer in murine models: A review

“…MS-based methods, however, usually require more labor-intensive sample preparation and do not allow for sample recovery [9]. In metabolomics, analysis of complex mixtures by NMR and/or MS is aided by multivariate analysis methods, in order to identify meaningful metabolic variations associated, for instance, to diseases such as cancer [10,11]. Figure 1 shows a typical metabolomics workflow applicable to biological samples.…”