1972
DOI: 10.1016/0022-2836(72)90374-9
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Nuclear magnetic resonance study of lecithin-cholesterol interactions

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Cited by 236 publications
(95 citation statements)
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“…lipid fatty acyl chains in the presence of cholesterol [2,3]. Moreover, using differential scanning calorimetry a decrease of order has been detected in the gel phase [4].…”
Section: Ln~mentioning
confidence: 99%
“…lipid fatty acyl chains in the presence of cholesterol [2,3]. Moreover, using differential scanning calorimetry a decrease of order has been detected in the gel phase [4].…”
Section: Ln~mentioning
confidence: 99%
“…It was recently suggested [5][6][7] that in bilayers of phosphatidylcholine and cholesterol a phase separation occurs at low cholesterol concentrations in that clusters of cholesterol-phosphatidylcholine complexes are present next to free phosphatidylcholine. If this lateral phase separation is comparable with that demonstrated in a mixture of phosphatidylcholines that shows monotectic behaviour this should be able to be visualized with freeze fracturing.…”
Section: The Influence Of Cholesterol On the Crystallization Behavioumentioning
confidence: 99%
“…Spectroscopic data reveal that cholesterol restricts the thermal motion of fatty acid chains in a phospholipid bilayer above the gel-to-liquid transition temperature (14)(15)(16), and this causes a "condensation effect" and decreases permeability (17). An increase in bilayer microviscosity evidently accounts for the inhibit'ry effect of cholesterol on fusion between plasma membranes of cultured muscle cells (18) and synthetic phospholipid membranes (19).…”
mentioning
confidence: 99%