133 Ba + has been identified as an attractive ion for quantum information processing due to the unique combination of its spin-1/2 nucleus and visible wavelength electronic transitions. Using a microgram source of radioactive material, we trap and laser-cool the synthetic A = 133 radioisotope of barium II in a radio-frequency ion trap. Using the same, single trapped atom, we measure the isotope shifts and hyperfine structure of the 6 2 P 1/2 ↔ 6 2 S 1/2 and 6 2 P 1/2 ↔ 5 2 D 3/2 electronic transitions that are needed for laser cooling, state preparation, and state detection of the clockstate hyperfine and optical qubits. We also report the 6 2 P 1/2 ↔ 5 2 D 3/2 electronic transition isotope shift for the rare A = 130 and 132 barium nuclides, completing the spectroscopic characterization necessary for laser cooling all long-lived barium II isotopes.Since the demonstration of the first CNOT gate over 20 years ago [1], trapped ion quantum information processing (QIP), including quantum simulation, has developed considerably [2], recently demonstrating fullyprogrammable quantum processors [3,4]. To date, qubits have been demonstrated in trapped ion hosts of all nonradioactive, alkaline-earth-like elements [1,[5][6][7][8][9][10][11][12]. These ions possess a simple electronic structure that facilitates straightforward laser cooling as well as quantum state preparation, manipulation, and readout via electromagnetic fields.For the coherent manipulation of qubits, the phase of this applied electromagnetic field must remain stable with respect to the qubit phase evolution. Thus, atomic hyperfine structure is a natural choice for the definition of a qubit, as these extremely long-lived states can be manipulated with easily-generated, phase-coherent microwave radiation. In particular, qubits defined on the hyperfine structure of ions with half-integer nuclear spin possess a pair of states with no projection of the total angular momentum (F ) along the magnetic field (m F = 0). These so-called "clock-state" qubits are well-protected from magnetic field noise and can yield coherence times exceeding 10 minutes [13,14]. Further, for these species, F = 0 ground and excited states only occur when the nuclear spin I = 1/2. This is desirable because the F = 0 ↔ F = 0 selection rule can be leveraged to produce fast, robust qubit state preparation and readout that relies solely on frequency selectivity [10,12].Among the alkaline-earth-like elements, only three (Cd, Hg, Yb) have naturally occurring I = 1/2 isotopes. Mercury and cadmium ions require lasers in the deep ultraviolet portion of the electromagnetic spectrum, making it difficult to integrate them into a large-scale QIP architecture. Since 171 Yb + has the longest laser-cooling wavelength at 370 nm, it has been used in a wide variety of groundbreaking QIP experiments [4,[15][16][17][18][19]. However, even at this ultraviolet wavelength, the use of photonics infrastructure developed for visible and infrared light is limited. For example, significant fiber attenuation limits t...