Nuclear organization and morphology of serotonergic neurons in the brain of the Nile crocodile, Crocodylus niloticus

Rodrigues, Stacey-Lee; Maseko, Busisiwe C.; Ihunwo, Amadi O.; Fuxé, Kjell; Manger, Paul R.

doi:10.1016/j.jchemneu.2007.08.007

Cited by 16 publications

(14 citation statements)

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“…The PVO system of CFScontacting neurons is present in adult non-mammalian vertebrates and in prototherian mammals (Vigh et al, 2004) and has been shown to contain 5-HT-ir perikarya in reptilians Rodrigues et al, 2008), in pigeons (Hirunagi et al, 1992;Challet et al, 1996), quails (Cozzi et al, 1991;Haida et al, 2004) and chickens Yamada et al, 1984;Hirunagi et al, 1992), as well as in monotreme mammals (Manger et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…circumventricular organ (the paraventricular organ, or PVO) of the posterior third ventricle exclusively, which appears to be an attribute unique to non-mammalian vertebrates (e.g., Ueda et al, 1984;Ekströ m and Ebbesson, 1989;Cozzi et al, 1991;Hirunagi et al, 1992;Challet et al, 1996;Dicke et al, 1997;Kaslin and Panula, 2001;Rink and Guo, 2004;Rodrigues et al, 2008) as well as to the monotreme (prototheria) hypothalamus (Manger et al, 2002).…”

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confidence: 99%

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Distribution of tryptophan hydroxylase-immunoreactive neurons in the brainstem and diencephalon of the pigeon (Columba livia)

Meneghelli

Rocha

Mengatto

et al. 2009

Journal of Chemical Neuroanatomy

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Distribution of tryptophan hydroxylase-immunoreactive neurons in the brainstem and diencephalon of the pigeon (Columba livia)

Meneghelli

Rocha

Mengatto

et al. 2009

Journal of Chemical Neuroanatomy

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“…In amniotes, two main clusters of 5-HT-ir cells are generally recognized, these are termed superior (rostral) raphe and inferior (caudal) raphe, respectively. Moreover, serotonergic cells laterally displaced into the reticular formation of amni-otes and anuran amphibians have been described [Lidov and Molliver, 1982;Yamada et al, 1984;Wolters et al, 1985;Aitken and Törk, 1988;Cozzi et al, 1991;Challet et al, 1996;Adli et al, 1999;Rodrigues et al, 2008]. Displaced 5-HT cells in the reticular region are also characteristic of elasmobranchs [Stuesse et al, 1995;Carrera et al, 2008] and four main groups have been reported in zebrafish [Ekström and Van Veen, 1984;Ekström et al, 1985;Ekström, 1994;Kaslin and Panula, 2001].…”

Section: Brainstemmentioning

confidence: 97%

“…Comparatively, similar serotonergic CSF-contacting cells have been described in the basal hypothalamus of all groups of anamniotes and in most reptiles studied (lizards and turtles), although a different terminology has been used [hypothalamic periventricular organ, PVO, nucleus organi paraventricularis; Parent and Poitras, 1974;Marschall, 1980;Ueda et al, 1983;Wolters et al, 1985;Smeets and Steinbush, 1988;Challet et al, 1991]. Notable exceptions have been reported for the chameleon Chameleo chameleo, which completely lacks serotonergic hypothalamic cells [Bennis et al, 1990], and the Nile crocodile Crocodylus niloticus, which possesses hypothalamic cells but not in the ependymal wall of the infundibular recess [Rodrigues et al, 2008]. Similar to observations in reptiles, the presence of 5-HT cells in the periventricular organ of the infundibular recess of birds has been detected in pigeons [Challet et al, 1996].…”

Section: Forebrainmentioning

confidence: 99%

“…The presence of this serotonergic cell group in lampreys, elasmobranchs, and the basal cladistians suggests its ancient significance, and similar cell populations are also present in most fish groups [Lillesaar, 2011;, although they could have been lost in chondrosteans [Adrio et al, 1999] and some teleosts [Rodríguez-Gó-mez et al, 2000]. In clear contrast, all tetrapods lack this serotonergic group, with the only puzzling exception of the Nile crocodile [Rodrigues et al, 2008].…”

Section: Forebrainmentioning

confidence: 99%

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Organization of the Serotonergic System in the Central Nervous System of Two Basal Actinopterygian Fishes: the Cladistians Polypterus senegalus and Erpetoichthys calabaricus

López¹,

González²

2014

Brain Behav Evol

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Cladistians (Polypteriformes) are currently considered basal to other living ray-finned fishes (actinopterygians), and their brain organization is therefore critical to providing information about the primitive neural characters that existed in the earliest ray-finned fishes. The organization of the serotonergic system in the brain has been carefully analyzed in most vertebrate groups, and in the present study we provide the first detailed information on the distribution of serotonergic cell bodies and fibers in the central nervous system of representative species of the two extant genera of cladistians, i.e. Polypterus senegalus and Erpetoichthys calabaricus, by means of immunohistochemistry against serotonin (5-HT). Distinct groups of immunoreactive cells were detected in the preoptic area, the hypothalamic paraventricular organ, the pineal organ, the pretectal region, the long column of the raphe in the rhombencephalic midline, the spinal cord, and amacrine cells in the inner nuclear layer of the retina. Fiber labeling was widely distributed in all main brain subdivisions but was more abundant in distinct pallial and subpallial areas, the preoptic area, the thalamus, the optic tectum, the tori semicircularis and lateralis, the rhombencephalic reticular formation, the nucleus of the solitary tract, and the dorsal aspect of the spinal cord. Our analysis makes it possible to establish which serotonergic structures characterized the earliest ray-finned fishes, and a comparison of these results with those from other classes of vertebrates, including a segmental analysis to correlate cell populations, reveals that most characteristics, such as the presence of serotonergic cells in the preoptic area and the basal hypothalamus, are preserved in all anamniotes. However, this system seems to be reduced in amniotes, mainly mammals, although important features are shared, such as the presence of serotonergic cells in the pineal organ, the retina, and the raphe nuclei.

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Immunohistochemical Localization of Somatostatin in the Brain of Chinese Alligator Alligator sinensis

Wang

Zhang

et al. 2016

The Anatomical Record

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In this study, the regional distribution and histological localization of somatostatin (SS) immunoreactive (IR) perikarya and fibers was investigated for the first time in the brain of adult Chinese alligator by immunohistochemical method. The results showed SS-IR perikarya and fibers were widely distributed in various parts of the brain except for olfactory bulbs. In the telencephalon, SS-IR perikarya were predominantly located in the cellular layer and deep plexiform layer of dorsomedial and medial cortex, less in the dorsal and lateral cortex, while SS-IR fibers were found in all layers of the cerebral cortex. SS-IR perikarya and fibers were also detected in the dorsal ventricular ridge, hippocampus cortex, accessory olfactory bulb nuclearus, lenticular nucleus, and caudate nucleus. In the diencephalon, SS-IR perikarya and fibers were mainly present in supraoptic nucleus, paraventricular nucleus of hypothalamus, recessus infundibular nucleus, median eminence, the pineal gland and pituitary gland, in which the IR-fibers were abundant, appearing dot-shaped and varicosity-like. In the mesencephalon, they were present in tectum cortex, ependyma of cerebral aqueduct and the periaqueductal grey matter. Additionally, they were also detected in Purkinje's cellular layer of cerebellum, in the reticularis nucleus and raphe nucleus of medulla oblongata. The distribution pattern of SS-IR perikarya and fibers in the brain of Chinese alligator is generally similar to that reported in other reptiles, but also has some specific features. The wide distribution indicated that SS might be a neurotransmitter or neuromodulator which acts on many kinds of target cells with a wide range of physiological functions. Anat Rec, 300:507-519, 2017. © 2016 Wiley Periodicals, Inc.

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Nuclear organization and morphology of serotonergic neurons in the brain of the Nile crocodile, Crocodylus niloticus

Cited by 16 publications

References 50 publications

Distribution of tryptophan hydroxylase-immunoreactive neurons in the brainstem and diencephalon of the pigeon (Columba livia)

Distribution of tryptophan hydroxylase-immunoreactive neurons in the brainstem and diencephalon of the pigeon (Columba livia)

Organization of the Serotonergic System in the Central Nervous System of Two Basal Actinopterygian Fishes: the Cladistians <b><i>Polypterus senegalus</i></b> and <b><i>Erpetoichthys calabaricus</i></b>

Immunohistochemical Localization of Somatostatin in the Brain of Chinese Alligator Alligator sinensis

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