Nuclear Quadrupole Resonance spectroscopy in studies of biologically active molecular systems—a review

The application of frequency swept pulses for the acquisition of nuclear quadrupole resonance spectra

“…For these reasons, NQR spectroscopy has found applications in a wide range of areas such as inorganic chemistry, materials science and pharmaceuticals [6][7][8][9][10][11][12][13][14][15].…”

“…1b) have also been employed for signal enhancement [30,31]. These sequences have enabled the acquisition of NQR spectra of nuclei such as 14 N, which typically possesses low resonance frequencies and inherently low signal to noise (S/N) [21,22,32,33]. It should also be noted that CPMG-type sequences have found applications for the signal enhancement of solid-state NMR spectra [34][35][36][37][38].…”

Towards Understanding Drugs on the Molecular Level to Design Drugs of Desired Profiles

“…A combination of experimental and theoretical techniques has certainly much to offer for the studies of drugs or potential drugs in early phases of drug research. Their capabilities in particular when applied to the known drugs, have been well documented in literature [92,99,101,104,105,148,[156][157][158][159][160][161][184][185][186][187][188][189]. Although in some fields the NMR or NQR are not competitive to IR, UV or XRD the examples of combined studies given above show that both techniques have a potential to elicit structural and physico-chemical information about a molecule of dug, target or the interaction drug-target.…”

Repetitive experiments of one or two-pulse sequences in NQR of spins I=3/2: Liouville space, steady-state, Ernst angle and optimum signal

“…Since its discovery in the 1950s [3], [4], [5], [6], [7], [8] , it is widely used in condensed-matter physics, for instance for the study of phase transitions or polymorphism, and has also biophysical or pharmaceutical applications [9], [10], [11], [12], [13], [14].…”