We review a unique prediction of Quantum Chromo Dynamics, called color transparency (CT), where the final (and/or initial) state interactions of hadrons with the nuclear medium must vanish for exclusive processes at high momentum transfers. We retrace the progress of our understanding of this phenomenon, which began with the discovery of the J/ψ meson, followed by the discovery of high energy CT phenomena, the recent developments in the investigations of the onset of CT at intermediate energies and the directions for future studies.