Nucleation and growth of apatite on NaOH-treated PEEK, HDPE and UHMWPE for artificial cornea materials

Pino, M.; Stingelin, Natalie; Tanner, K.E.

doi:10.1016/j.actbio.2008.05.004

Cited by 71 publications

(44 citation statements)

References 44 publications

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“…During apatite formation the presence of Ca and P along with other elements such as Na, K, Mg, C, O and Cl was also observed by EDX as reported after the immersions [31]. The precipitation of apatite over the chitosan film called primary apatite accelerates further with secondary apatite formation during the second week of immersion [19].…”

Section: Sem and Edx Analysismentioning

confidence: 62%

Mineralization of pristine chitosan film through biomimetic process

Baskar

Balu

Kumar

2011

International Journal of Biological Macromolecules

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Section: Sem and Edx Analysismentioning

confidence: 62%

Mineralization of pristine chitosan film through biomimetic process

Baskar

Balu

Kumar

2011

International Journal of Biological Macromolecules

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“…The silanes were bonded to a previously activated (KOH treatment) thermoplastic polymer. The effectiveness of KOH treatment to modified PEEK [46,47] and PETE [48,49,50] is very well-known, especially for composites formation. The thermoplastic substrates were cleaned by sonication and then rinsed with propanol and distilled water.…”

Section: Activation Processmentioning

confidence: 99%

Large areain situfabrication of poly(pyrrole)-nanowires on flexible thermoplastic films using nanocontact printing

García‐Cruz¹,

Lee²,

Marote³

et al. 2016

Mater. Res. Express

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Abstract:Highly efficient nano-engineering tools will certainly revolutionize the biomedical and sensing devices research and development in the years to come. Here, we present a novel high performance conducting poly(pyrrole) nanowires (PPy-NW) patterning technology on thermoplastic surfaces (poly(ethylene terephthalate (PETE), poly(ethylene 2,6-naphthalate (PEN), polyimide (PI), and cyclic olefin copolymer (COC)) using nanocontact printing and controlled chemical polymerization (nCP-CCP) technique. The technique uses a commercial compact disk (CD) as a template to produce nanopatterned polydimethylsiloxane (PDMS) stamps. The PDMS nanopatterned stamp was applied to print the PPy-NWs and the developed technology of nCP-CCP produced 3D conducting nanostructures. This new and very promising nanopatterning technology was achieved in a single step and with a low cost of fabrication over large areas.

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“…It is evident, though, that various parameters may be varied in these procedures, including NaOH concentration, immersion time in NaOH and SBF, etc. The focus of the present study was therefore to further elucidate the effect of highly concentrated NaOH pre-treatments on the polymer films for stimulating apatite deposition from 1.5 SBF (our previous work has shown that low concentrated NaOH pre-treatments are ineffective [38] ) and to investigate the apatite deposition over immersion times in 1.5 SBF of up to 30 days (in previous work, the data obtained was restricted to 15-18 days immersion [38] ). The influence of these treatments on wettability and polymer surface morphologies were also analyzed.…”

mentioning

confidence: 99%

Apatite Deposition on NaOH‐Treated PEEK and UHMWPE Films for Sclera Materials in Artificial Cornea Implants

et al. 2010

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Cornea implants consist of a clear optic portion with a surrounding ring known as the skirt, which needs to integrate with the sclera. However, currently used skirt materials lead to poor tissue integration. Improvements in this respect may be achieved by using a bioactive skirt material that adapts to the metabolic activity of the cornea. Polyether etherketone (PEEK) and ultra‐high molecular weight polyethylene (UHMWPE) might provide interesting alternatives, if they can be rendered bioactive. We, therefore, investigated the potential of surface‐modifying PEEK and UHMWPE films through the use of a two‐step treatment. This process involved a suitable chemical surface modification (via immersion in NaOH), with subsequent formation of apatite layers on the polymers' surfaces through exposure to supersaturated simulated body fluid (1.5 SBF). In the present work the effect of 5 and 10 M NaOH on formation of the apatite layer has been investigated with regard to wettability and topography features. In addition, the chemical stability of the apatite layer formed has been analyzed. Our data demonstrate that with an increase in NaOH concentration the wettability of the polymer increased, whilst some changes to the polymer film topography (increase/decrease in roughness) were observed. Most beneficially, the apatite layer that subsequently was grown on pre‐treated PEEK and UHMWPE films through immersion in 1.5 SBF contained phosphate and carbonate ions, in similar ratios to those found in the apatite in dentine, thus, promising good in vivo bioactivity of these polymer films—a necessity if they are to be integrated into artificial cornea.

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Nucleation and growth of apatite on NaOH-treated PEEK, HDPE and UHMWPE for artificial cornea materials

Cited by 71 publications

References 44 publications

Mineralization of pristine chitosan film through biomimetic process

Mineralization of pristine chitosan film through biomimetic process

Large areain situfabrication of poly(pyrrole)-nanowires on flexible thermoplastic films using nanocontact printing

Apatite Deposition on NaOH‐Treated PEEK and UHMWPE Films for Sclera Materials in Artificial Cornea Implants

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