Nucleation control of quantum dot synthesis in a microfluidic continuous flow reactor

Abstract

The use of microfluidics in chemical synthesis is topical due to the potential to improve reproducibility and the ability promptly interrogate a wide range of reaction parameters, the latter of which is necessary for the training of artificial intelligence (AI) algorithms. Applying microfluidic techniques to semiconductor nanocrystals, or quantum dots (QDs), is challenging due to the need for a high-temperature nucleation event followed by particle growth at lower temperatures. Such a high-temperature gradient can be realized using complex, segmented microfluidic reactor designs, which represents an engineering approach. Here, an alternative chemical approach is demonstrated using the cluster seed method of nanoparticle synthesis in a simple microfluidic reactor system. This enables quantum dot nucleation at lower temperatures due to the presence of molecular organometallic compounds (NMe4)4[Cd10Se4(SPh)16] and (NMe4)4[Zn10Se4(SPh)16]. This integration of cluster seeding with microfluidics affords a new mechanism to tailor the reaction conditions for optimizing yields and tuning product properties.

Dynamic Flow Control over Optical Properties of Liquid Crystal–Quantum Dot Hybrids in Microfluidic Devices

“…Integrating microfluidic devices with optically active functional nanomaterials such as quantum dots (QD) makes a substantial contribution to advancing applications of fluidic micromachines in nanotechnology [ 14 , 15 ], chemical and bioanalysis [ 16 , 17 , 18 ], the synthesis of target drug delivery systems [ 19 , 20 , 21 ] or nanomedicine [ 22 ]. Current research activities also focus on fine-tuning the microscale synthesis of quantum dots [ 23 , 24 , 25 , 26 ] and conjugating them with soft matter [ 15 , 21 , 27 ].…”