Nuf and Rip11 requirement for polarity determinant recycling during<i>Drosophila</i>development

Calero-Cuenca, Francisco J.; Sotillos, Sol

doi:10.1080/21541248.2016.1235386

Cited by 5 publications

(3 citation statements)

References 34 publications

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“…7). Rab11 has multiple effectors (Dusty-like protein, Rip11) in addition to NUF (Nagaraj & Adler, 2012;Calero-Cuenca & Sotillos, 2018). These other effectors may be involved in PTTH secretion.…”

Section: Discussionmentioning

confidence: 99%

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Locations of Rab, Allatotropin, Prothoracicotropic hormone and Period in the larval brain, corpus allatum and frontal ganglion of Bombyx mori

Matsui¹,

TOKUSHIGE²,

Mizoguchi³

et al. 2023

Eur. J. Entomol.

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Section: Discussionmentioning

confidence: 99%

“…NUF is a Rab11 effector protein that is important in controlling the transmission of several intracellular cargos (Riggs et al, 2007;Calero-Cuenca & Sotillos, 2018).…”

Section: Anti-b Mori Nuf Antibodies and Location Of Nuf Immunoreactivitymentioning

confidence: 99%

Locations of Rab, Allatotropin, Prothoracicotropic hormone and Period in the larval brain, corpus allatum and frontal ganglion of Bombyx mori

Matsui¹,

TOKUSHIGE²,

Mizoguchi³

et al. 2023

Eur. J. Entomol.

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“…One study demonstrated that a conditional knockout of Rab11fip5 in mice causes the failure of AMPA receptor recycling, resulting in severe long-term neuronal depression ( Bacaj et al, 2015 ). Another study suggested that Rab11fip5 is involved in aPKC recycling to regulate cell polarity in Drosophila ectoderm ( Calero-Cuenca and Sotillos, 2018 ).…”

Section: Discussionmentioning

confidence: 99%

Rab11fip5 regulates telencephalon development via ephrinB1 recycling

et al. 2021

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Rab11 family-interacting protein 5 (Rab11fip5) is an adaptor protein that binds to the small GTPase Rab11, which has an important function in endosome recycling and trafficking of cellular proteins to the plasma membrane. Rab11fip5 is involved in many cellular processes, such as cytoskeleton rearrangement, iron uptake and exocytosis in neuroendocrine cells, and is also known as a candidate gene for autism-spectrum disorder. However, the role of Rab11fip5 during early embryonic development is not clearly understood. In this study, we identified Rab11fip5 as a protein that interacts with ephrinB1, a transmembrane ligand for Eph receptors. The PDZ binding motif in ephrinB1 and the Rab-binding domain in Rab11fip5 are necessary for their interaction in a complex. EphrinB1 and Rab11fip5 display overlapping expression in the telencephalon of developing amphibian embryos. The loss of Rab11fip5 function causes a reduction in telencephalon size and a decrease in the expression level of ephrinB1. Moreover, morpholino oligonucleotide-mediated knockdown of Rab11fip5 decreases cell proliferation in the telencephalon. The overexpression of ephrinB1 rescues these defects, suggesting that ephrinB1 recycling by the Rab11/Rab11fip5 complex is crucial for proper telencephalon development.

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Src family kinases (SFKs) and cell polarity in the testis

Xiao

et al. 2018

Seminars in Cell & Developmental Biology

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Non-receptor Src family kinases (SFKs), most notably c-Src and c-Yes, are recently shown to be expressed by Sertoli and/or germ cells in adult rat testes. Studies have shown that SFKs are involved in modulating the cell cytoskeletal function, and involved in endocytic vesicle-mediated protein endocytosis, transcytosis and/or recycling as well as intracellular protein degradation events. Furthermore, a knockdown to SFKs, in particular c-Yes, has shown to induce defects in spermatid polarity. These findings, coupled with emerging evidence in the field, thus prompt us to critically evaluate them to put forth a developing concept regarding the role of SFKs and cell polarity, which will become a basis to design experiments for future investigations.

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Nuf and Rip11 requirement for polarity determinant recycling duringDrosophiladevelopment

Cited by 5 publications

References 34 publications

Locations of Rab, Allatotropin, Prothoracicotropic hormone and Period in the larval brain, corpus allatum and frontal ganglion of Bombyx mori

Locations of Rab, Allatotropin, Prothoracicotropic hormone and Period in the larval brain, corpus allatum and frontal ganglion of Bombyx mori

Rab11fip5 regulates telencephalon development via ephrinB1 recycling

Src family kinases (SFKs) and cell polarity in the testis

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