Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study

Skarpsno, Eivind Schjelderup; Mork, Paul Jarle; Hagen, Knut; Nilsen, Tom Ivar Lund; Marcuzzi, Anna

doi:10.2147/nss.s284498

Cited by 15 publications

(10 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consistent with studies of insomnia variously defined, 1 , 4 , 5 , 32 we found participants with chronic DIMS demonstrated associations with multi-morbidity in adjusted models. Around half of those reporting chronic insomnia symptoms irrespective of the TIB criterion demonstrated poor health status and ever diagnosed chronic conditions (mental health and airway disorders).…”

Section: Discussionsupporting

confidence: 89%

“…Insomnia contributes to a considerable burden of physical and mental health problems, 1 including cardiovascular disease, 2 , 3 and chronic pain. 4 Insomnia is highly co-morbid with a number of psychiatric diseases, and increases the risk of incident major depressive disorder. 5 Insomnia also predicts earlier retirement 6 and accidents.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Insomnia Prevalence Varies with Symptom Criteria Used with Implications for Epidemiological Studies: Role of Anthropometrics, Sleep Habit, and Comorbidities

Appleton¹,

Reynolds²,

Gill³

et al. 2022

NSS

View full text Add to dashboard Cite

Introduction Estimating insomnia prevalence in epidemiological studies is hampered by variability in definitions and interpretation of criteria. We addressed the absence of a population-based estimate of insomnia in Australia using the widely accepted contemporary International Classification of Sleep Disorders (ICSD-3) criteria, which includes sleep opportunity, and has not been applied in studies to date. Consistent use of these criteria across epidemiological studies, however, requires evidence of the clinical utility of a sleep opportunity criterion for targeting strategies. Methods A cross-sectional national on-line survey (2019 Sleep Health Foundation Insomnia Survey) of Australian adults (18–90 years, n = 2044) was conducted. Chronic insomnia was defined as sleep symptoms and daytime impairment experienced ≥3 times per week, and present for ≥3 months, with adequate sleep opportunity (time in bed (TIB) ≥7.5 hrs). Self-rated general health (SF-1) and ever diagnosed health conditions (including sleep disorders) were assessed. Results Chronic difficulties initiating and maintaining sleep and daytime symptoms (n = 788) were more common in females (41.5%) than males (35.3%), p = 0.004. Excluding participants reporting frequent pain causing sleep disruption and TIB <7.5 hrs generated an insomnia disorder estimate of 25.2% (95% CI: 22.5–28.2) in females and 21.1% (18.4–23.9) in males [23.2% (21.2–25.2) overall]. This compares with 8.6% (7.3–10.0) with insomnia symptoms and TIB <7.5 hrs and 7.5% (6.4–8.7%) ever diagnosed with insomnia. Insomnia symptom groups with TIB <7.5 and ≥7.5 hours demonstrated similar odds of reporting fair/poor health [odds ratio (OR): 3.2 (95% CI: 2.1–4.8) and 2.9 (95% CI: 2.2–3.9) respectively], ≥1 mental health condition, ≥1 airway disease, and multimorbidity. Conclusion Adults with significant sleep and daytime symptomatology and TIB <7.5 hrs did not differ clinically from those with insomnia disorder. Consideration of criteria, particularly adequate sleep opportunity, is required to consistently identify insomnia, and establish health correlates in future epidemiological studies. Further evaluation of the clinical utility of the sleep opportunity criterion is also required.

show abstract

Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Insomnia Prevalence Varies with Symptom Criteria Used with Implications for Epidemiological Studies: Role of Anthropometrics, Sleep Habit, and Comorbidities

Appleton¹,

Reynolds²,

Gill³

et al. 2022

NSS

View full text Add to dashboard Cite

show abstract

“…Moreover, it is well established that insomnia is a strong risk factor for anxiety and depression [15,16]. Insomnia symptoms are frequent in people with musculoskeletal pain [17][18][19] and these conditions appear to be bi-directionally related, where pain increases the risk of insomnia [20] and vice versa [21]. The pathways linking insomnia and musculoskeletal pain with mood disorders are thought to be complex and include altered immune responses [22][23][24][25], neurobiological changes such as dysregulations in monoamine levels [26], alteration in brain regions involved in emotional processing [27], as well as psychological stressors such as perceived stress, loss of control, maladaptive coping, and social support [28].…”

Section: Introductionmentioning

confidence: 99%

The interplay between multisite pain and insomnia on the risk of anxiety and depression: the HUNT study

et al. 2022

Self Cite

View full text Add to dashboard Cite

Background Chronic musculoskeletal pain and insomnia frequently co-occur and are known independent risk factors for anxiety and depression. However, the interplay between these two conditions on the risk of anxiety and depression has not been explored. Methods A population-based prospective study of 18,301 adults in the Norwegian HUNT Study without anxiety or depression at baseline (2006–2008). We calculated adjusted risk ratios (RRs) with 95% confidence intervals (CIs) for anxiety and/or depression at follow-up (2017–2019), associated with i) number of chronic pain sites, and ii) chronic pain and insomnia symptoms jointly. Results At follow-up, 2155 (11.8%) participants reported anxiety and/or depression. The number of pain sites was positively associated with risk of anxiety and/or depression (Ptrend, < 0.001). Compared to people without chronic pain and insomnia symptoms, people with ≥5 pain sites and no insomnia symptoms had a RR of 1.52 (95% CI: 1.28 to 1.81) for anxiety and/or depression, those with no chronic pain but with insomnia had a RR of 1.78 (95% CI: 1.33 to 2.38), whereas the RR among people with both ≥5 pain sites and insomnia was 2.42 (95% CI: 1.85 to 3.16). We observed no synergistic effect above additivity for the combination of ≥5 pain sites and insomnia on risk of anxiety and/or depression. Conclusions This study shows that people with multisite chronic pain who also suffer from insomnia are at a particularly high risk for anxiety and/or depression, suggesting that insomnia symptoms are important contributors to the association between multisite pain and common mental health problems.

show abstract

“…For instance, although the data in the current study show that insomnia is prevalent among sick-listed workers with musculoskeletal pain or mental health conditions, it is well established that insomnia is bi-directionally related with pain and mental health conditions. 16 , 21 , 22 Supplementary analyses with additional adjustment for depression had negligible influence on our estimates. However, the study design in the current study cannot verify the causal pathways between these conditions throughout the follow-up, that is, which factors that are likely to influence each other.…”

Section: Discussionmentioning

confidence: 92%

“…12 Insomnia is common among people with musculoskeletal disorders 13 or mental health disorders, 14 and it plays an important role in the risk and progression of these conditions. [15][16][17][18][19][20] Additionally, these conditions appear to be bidirectionally related, where musculoskeletal pain and mental health disorders also increase the risk of insomnia. 21,22 Inpatient rehabilitation programs incorporate principles known to be helpful for good sleep quality, 23,24 such as physical exercise, 25,26 psychoeducational sessions, including sleep education, and fixed schedules.…”

Section: Introductionmentioning

confidence: 99%

Insomnia is Associated with the Effect of Inpatient Multimodal Occupational Rehabilitation on Work Participation in Workers with Musculoskeletal or Mental Health Disorders: Secondary Analyses of a Randomized Clinical Trial

Skarpsno¹,

Gismervik²,

Fimland³

et al. 2021

NSS

Self Cite

View full text Add to dashboard Cite

Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study

Cited by 15 publications

References 43 publications

Insomnia Prevalence Varies with Symptom Criteria Used with Implications for Epidemiological Studies: Role of Anthropometrics, Sleep Habit, and Comorbidities

Insomnia Prevalence Varies with Symptom Criteria Used with Implications for Epidemiological Studies: Role of Anthropometrics, Sleep Habit, and Comorbidities

The interplay between multisite pain and insomnia on the risk of anxiety and depression: the HUNT study

Insomnia is Associated with the Effect of Inpatient Multimodal Occupational Rehabilitation on Work Participation in Workers with Musculoskeletal or Mental Health Disorders: Secondary Analyses of a Randomized Clinical Trial

Contact Info

Product

Resources

About