Number of metastatic lymph nodes as determinant of outcome after salvage radical prostatectomy for radiation-recurrent prostate cancer

Gugliemetti, G.; Sukhu, Ranjit; Baenas, M.A. Conca; Meeks, Joshua J.; Sjoberg, Daniel D.; Eastham, James A.; Scardino, Peter T.; Touijer, Karim

doi:10.1016/j.acuroe.2016.06.004

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Circulating Tumor Cell Therapeutics In Tumor-draining Lymph ...1

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2018

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“…Among patients with lung, breast, and colorectal cancers, around 29-37% are diagnosed with metastases in their lymph nodes (67). Therefore, metastatic lymph node prognosis is an important indicator of metastatic burden pre-and posttreatment in many types of cancer therapy (118)(119)(120)(121).…”

Section: Circulating Tumor Cell Therapeutics In Tumor-draining Lymph ...mentioning

confidence: 99%

Circulating Tumor Cells: Diagnostic and Therapeutic Applications

Lin

Cao

Nagrath

et al. 2018

Annu. Rev. Biomed. Eng.

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Metastasis contributes to poor prognosis in many types of cancer and is the leading cause of cancer-related deaths. Tumor cells metastasize to distant sites via the circulatory and lymphatic systems. In this review, we discuss the potential of circulating tumor cells for diagnosis and describe the experimental therapeutics that aim to target these disseminating cancer cells. We discuss the advantages and limitations of such strategies and how they may lead to the development of the next generation of antimetastasis treatments.

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Section: Circulating Tumor Cell Therapeutics In Tumor-draining Lymph ...mentioning

confidence: 99%